Rate My Professor Drewry David

Drewry's research centers on the medicinal chemistry of protein kinases, including the discovery of chemical probes for understudied kinases and development of kinase chemogenomic sets such as the Kinase Chemogenomic Set (KCGS). His lab, trained in synthetic organic chemistry, designs and optimizes small molecules to address biological questions, particularly in rare cancers like chordoma, fibrolamellar cancer, diffuse intrinsic pontine glioma, and desmoplastic small round cell tumor, involving target discovery, validation, and lead optimization. Key publications include "Structural insights into human brachyury DNA recognition and discovery of progressible binders for cancer therapy" (Nature Communications, 2025), "How many kinases are druggable? A review of our current understanding" (Biochemical Journal, 2023), "SGC-CAMKK2-1: A Chemical Probe for CAMKK2" (Cells, 2023), and "The Kinase Chemogenomic Set (KCGS): an open science resource for kinase vulnerability identification" (International Journal of Molecular Sciences, 2021). Awards include the GlaxoSmithKline Silver Award (2010), Chordoma Foundation Uncommon Collaboration Award (2016), UNC Junior Faculty Development Award (2017), and UNC Lineberger Innovation Award (2022). As a principal architect of SGC-UNC's research strategy, Drewry advances open collaborative networks for target discovery and chemical biology in oncology.