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Professor Atsushi Iwama is a Professor at the Institute of Medical Science, The University of Tokyo, where he heads the Division of Stem Cell and Molecular Medicine. He is a graduate of the School of Medicine at Niigata University. After engaging in medical practice for five and a half years, he obtained a PhD from the School of Medicine at Kumamoto University in 1996. He was appointed to his current position in 2005 and served as Director of the Center for Regenerative Therapeutics starting in 2015. He has also served as Dean of the Institute of Medical Science.
Professor Iwama specializes in stem cell biology, hematology, and oncology. His research focuses on the molecular mechanisms of self-renewal and multi-lineage differentiation of hematopoietic stem cells, with emphasis on epigenetic regulation including DNA and histone modifications and higher-order chromatin architecture. He investigates how deregulated hematopoietic stem cell functions contribute to aging and the development of age-related hematological malignancies. Since 2014, he has served as representative for the Research on Innovative Areas project on Stem Cell Aging and Diseases. Professor Iwama has contributed extensively to the fields of medicine, biochemistry, and genetics through numerous publications and research leadership roles.
University of Tokyo researchers uncover how MLKL protein impairs stem cell function via mitochondrial damage, offering new avenues for age-related blood disorders in Japan's aging society.
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