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About Bengt
Bengt Fadeel, MD, PhD, is Professor of Medical Inflammation Research at Karolinska Institute. He received his MD in 1997 and PhD in 1999 from Karolinska Institutet, with his doctoral thesis entitled "Mechanisms and mediators of apoptosis: with special reference to hematological disorders." He completed his clinical internship at Karolinska University Hospital and obtained board certification as a physician in 2001. Fadeel was appointed Docent in 2004 and Full Professor in 2010. He has served as Vice Chairman of the Institute of Environmental Medicine from 2009 to 2013 and since 2023, and as Head of the Unit of Molecular Toxicology. From 2011 to 2016, he was Foreign Adjunct Professor of Environmental and Occupational Health at the University of Pittsburgh. He previously held a national senior investigator award from the Swedish Research Council, the only such position in inflammation research. Fadeel chaired SweNanoSafe, a national platform for nanosafety, and is a member of the OECD WPMN steering group on advanced materials.
Fadeel's research in the Unit of Molecular Toxicology centers on molecular and biochemical processes induced by toxicants, with a focus on engineered nanomaterials including graphene oxide, MXenes, nanodiamonds, and transition metal dichalcogenides. His studies explore nanomaterial interactions with immune cells such as macrophages, dendritic cells, and neutrophils, including interferon responses, inflammasome activation, biodegradation, and microbiome-dependent immune effects. Key publications include "Graphene oxide elicits microbiome-dependent type 2 immune responses via the aryl hydrocarbon receptor" (Nature Nanotechnology, 2023), "Exploiting Mass Spectrometry to Unlock the Mechanism of Nanoparticle-Induced Inflammasome Activation" (ACS Nano, 2023), "Advanced tools for the safety assessment of nanomaterials" (Nature Nanotechnology, 2018), and "Safety Assessment of Graphene-Based Materials: Focus on Human Health and the Environment" (ACS Nano, 2018). With over 48,000 citations, his work has advanced nanotoxicology and nanomedicine. Awards include the Environmental Medicine Prize (2011), Fellow of the Academy of Toxicological Sciences (2012), and Member of Academia Europaea (2024). He is Editor-in-Chief of Frontiers in Toxicology and Associate Editor of Toxicological Sciences.
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