Rate My Professor C Vignesh Kumar

Dr. C. Vignesh Kumar serves as an Assistant Professor in the Department of Biotechnology at PSG College of Technology, Coimbatore, having joined on July 1, 2019. He possesses a B.Tech., M.Tech., and Ph.D., with a total professional experience of 12 years and 4 months, comprising 3 years and 7 months in teaching and 8 years and 9 months in research. His fields of specialization are Biochemistry, Biophysics, Protein Engineering, and Bio-analytical Methods. He imparts instruction in various undergraduate and postgraduate courses, including Microbiology and Cell Biology Lab, Biochemistry Lab, Analytical Methods and Instrumentation, Analytical Methods and Instrumentation Lab, Downstream Processing Lab, Analytical Instrumentation Techniques, Instrumental Methods and Analysis Lab, and Protein Chemistry and Engineering.

Dr. Vignesh Kumar's research interests include Aging, Cellular Proteostasis, Downstream Processing, protein chaperones such as DnaK, Sse1, Hsp110, substrate-chaperone interactions, protein aggregation and disaggregation, and endoplasmic reticulum stress. He has published 8 papers in international journals and co-authored the book chapter 'Hsp70: A Multi-Tasking Chaperone at the Crossroad of Cellular Proteostasis' in Regulation of Heat Shock Protein Responses, Heat Shock Proteins Vol. 13 (Springer, pp. 251-274, 2018). Key publications encompass 'Monitoring conformational heterogeneity of the lid of DnaK substrate-binding domain during its chaperone cycle' (The FEBS Journal, 2016), 'Information encoded in non-native states drives substrate-chaperone pairing' (Structure, 2012), 'Unique structural modulation of a non-native substrate by cochaperone DnaJ' (Biochemistry, 2013), 'Interdomain communication suppressing high intrinsic ATPase activity of Sse1 is essential for its co-disaggregase activity with Ssa1' (The FEBS Journal, 2020), and 'Sse1, Hsp110 chaperone of yeast, controls the cellular fate during endoplasmic reticulum stress' (G3: Genes, Genomes, Genetics, 2024). His scholarly output has accumulated 151 citations. Additionally, he is the Principal Investigator for a DRDO-sponsored research project.