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Christine L. Cain, DVM, DACVD, is an Associate Professor of Dermatology and Allergy at the University of Pennsylvania School of Veterinary Medicine, holding a clinician-educator appointment in the Department of Clinical Sciences and Advanced Medicine. She earned a BS in Biological Sciences from Cornell University in 2003 and a DVM from The Ohio State University College of Veterinary Medicine in 2006. She then completed a rotating internship in small animal medicine and surgery at Red Bank Veterinary Hospital from 2006 to 2007, followed by a residency in dermatology and allergy at the University of Pennsylvania School of Veterinary Medicine from 2007 to 2010. Upon completing her residency, she achieved board certification as a Diplomate of the American College of Veterinary Dermatology in 2010. In her role, Dr. Cain provides clinical expertise in dermatology and allergy services at Ryan Hospital, focusing on food and skin allergies, ear infections, and skin infections. She has served as chair of search committees for faculty positions such as Assistant/Associate Professor of Small Animal Internal Medicine within the School of Veterinary Medicine.
Dr. Cain's academic interests lie in infectious diseases, particularly staphylococcal infections encompassing epidemiology, clinical management, and antimicrobial stewardship, as well as immune-mediated diseases. Her research profile features 24 publications with 611 citations. Key contributions include 'Fosmidomycin for the Treatment of Canine Otitis Externa: A Randomised, Double-Blinded, Controlled ‘Split Body’ Clinical Trial' (2026), 'Treatment of Reactive Histiocytosis With Oclacitinib: A Retrospective Case Series of 10 Dogs' (2026), 'Clinical Features, Treatment and Outcomes of Dogs With Psoriasiform Lichenoid Dermatosis Associated With Calcineurin Inhibitor Therapy' (2025), 'Longitudinal evaluation of the cutaneous and rectal microbiota of German shepherd dogs with perianal fistulas undergoing therapy with ciclosporin and ketoconazole' (2024), 'The otic microbiota and mycobiota in a referral population of dogs in eastern USA with otitis externa' (Veterinary Dermatology, 2020), 'Discriminatory features of acute eosinophilic dermatitis with oedema (Wells-like syndrome) and sterile neutrophilic dermatosis (Sweet’s-like syndrome) in dogs' (Veterinary Dermatology, 2019), 'Canine Perianal Fistulas: Clinical Presentation, Pathogenesis, and Management' (The Veterinary Clinics of North America. Small Animal Practice, 2019), 'Clinical and histopathological features of Burkholderia cepacia complex dermatitis in dogs: a series of four cases' (Veterinary Dermatology, 2018), 'Clinical and histologic features of acute-onset erythroderma in dogs with gastrointestinal disease: 18 cases (2005-2015)' (Journal of the American Veterinary Medical Association, 2017), and 'Skin as a marker of general feline health: Cutaneous manifestations of infectious disease' (Journal of Feline Medicine and Surgery, 2017). These works advance understanding and treatment of dermatological conditions in companion animals.