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Associate Professor Craig Marshall is an academic in the Department of Biochemistry at the University of Otago, within the School of Biomedical Sciences and Faculty of Biomedical Sciences, Division of Health Sciences. He obtained his BSc (Hons) and PhD from the University of Otago, with the PhD awarded in 1988 for the thesis 'Structures of the haemoglobins of the brine shrimp, Artemia: an examination of their properties and synthesis'. Marshall has maintained a long-term academic career at the University of Otago, contributing to research and supervision in biochemistry.
His research interests lie in the biochemistry, physiology, and ecology of cold adaptation, including structural and functional adaptations of enzymes in Antarctic fish relative to temperate counterparts, impacts of low temperatures on protein structure and function, mechanisms of ligand-enzyme interactions, protein folding, and antifreeze glycopeptide structures elucidated by X-ray crystallography. Expertise areas cover cold adaptation and freezing tolerance in plants and animals, antifreeze compounds, evolution of Antarctic organisms, oyster biology, and Bonamia in oysters. Key publications include 'Cold-adapted enzymes' (Trends in Biotechnology, 1997), 'Laws of form revisited' (Nature, 2001, with M. Denton), 'Ice shell purification of ice-active compounds' (Methods in Molecular Biology, 2024, with J. Morris and M. Liddy), 'Insect freeze-tolerance Downunder: The microbial connection' (Insects, 2023, with M. Morgan-Richards et al.), 'Evidence for transition of metastable ice to hexagonal ice in bulk solutions at relatively high temperatures' (International Journal of Geosciences, 2020, with P.W. Wilson et al.), 'A nematode in the mist: Scottnema lindsayae is the only soil metazoan in remote Antarctic deserts' (Polar Research, 2019, with K. Zawierucha et al.), and 'Post-dormancy transcription and translation in the brine shrimp' (Artemia biology, 2018, with W.P. Tate). He has supervised numerous PhD and MSc theses, such as 'Ice Active Proteins from Cold Tolerant Organisms' (S.R. Clarke, 2016), 'Molecular Adaptation Mechanisms in the Antarctic Nematode Panagrolaimus davidi' (A. Seybold, 2016), 'Ice activities in New Zealand Chionochloa species' (H. Xiong, 2018), and others on photolyase expression, algal biotoxin metabolism, and cadmium binding in oysters. These contributions have enhanced understanding of molecular mechanisms for survival in extreme cold Antarctic and alpine environments.
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