T Cells Secrete DNA for Cancer Immunity | Weill Cornell Study | AcademicJobs
Weill Cornell researchers discover how T cells secrete DNA-laden extracellular vesicles to enhance antigen presentation and fight cold tumors like PDAC and GBM.
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Diao Liu serves as a Postdoctoral Associate in Pediatrics at Weill Cornell Medical College, a position he has held since 2024. He received his Ph.D. from the University of Pennsylvania in 2024 and his B.Sc. from Sun Yat-Sen University in China in 2018.
His research involves extracellular vesicles, exosomes, and mechanisms related to tumor progression and metastasis, with publications including "Stiff matrix induces exosome secretion to promote tumour growth" in Nature Cell Biology (2023), "A phosphoinositide switch mediates exocyst recruitment to multivesicular endosomes for exosome secretion" in Nature Communications (2023), and "TGM1/3-mediated transamidation of Exo70 promotes tumor metastasis upon LKB1 inactivation" in Cell Reports (2024). He contributed as co-first author to work on T cells secreting DNA-carrying vesicles to enhance immune responses against cancer, published in association with the Lyden lab at Weill Cornell Medicine.
Weill Cornell researchers discover how T cells secrete DNA-laden extracellular vesicles to enhance antigen presentation and fight cold tumors like PDAC and GBM.