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Dr. George Thanassoulis is a Professor of Medicine at McGill University in the Division of Cardiology and serves as Director of Preventive and Genomic Cardiology at the McGill University Health Centre. He completed his MD at the University of Toronto, followed by internal medicine and cardiology training at the University of Toronto and McGill University. He earned an MSc in Epidemiology and Biostatistics from McGill University. He then pursued a clinical fellowship in echocardiography at the Jewish General Hospital and a postdoctoral fellowship in Genomic and Cardiovascular Epidemiology at the NIH’s Framingham Heart Study.
His research focuses on cardiovascular prevention through genomic and molecular epidemiology, with particular emphasis on valvular heart disease, acute coronary syndromes, and Mendelian randomization. He co-led an international consortium that completed the first genome-wide association study for aortic valve disease, identifying lipoprotein(a) as a causal factor in its development. He is the principal investigator of the CIHR-funded Early Aortic Valve Lipoprotein(a) Lowering (EAVaLL) trial, which examines whether pharmacological Lp(a) lowering can reduce progression of aortic valve disease in genetically predisposed individuals. He also leads the MUHC Family Heart Clinic, addressing cardiovascular prevention for patients with premature coronary artery disease and their families.
McGill-led study in Nature Genetics uncovers 241 AS risk genes, enabling early detection and new therapies amid Canada's aging crisis.
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