Zeaxanthin Boosts Cancer Immunotherapy | UChicago Study
University of Chicago study reveals zeaxanthin enhances CD8+ T cells, boosting immunotherapy efficacy in cancer models. Explore mechanism, sources, trials.
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Dr. Jing Chen joined the University of Chicago in August 2020 as the Janet Davison Rowley Distinguished Service Professor of Medicine. He serves as Director of Basic and Translational Science in the Section of Hematology/Oncology, Associate Vice Chair for Translational Science in the Department of Medicine, inaugural director of the Cancer Metabolomics Research Center, and Associate Director for Translational Sciences at the University of Chicago Medicine Comprehensive Cancer Center. Prior to joining UChicago, Dr. Chen was professor and the R. Randall Rollins Chair in Oncology at the Emory University School of Medicine, where he also led the Cell and Molecular Biology Research Program at the Winship Cancer Institute of Emory University.
Dr. Chen earned his BS in Molecular Biology from the University of Science and Technology of China in 1994 and his PhD in Biochemistry and Cell Biology from Emory University in 2001. He completed postdoctoral training as an HHMI fellow in Cancer Biology at Harvard Medical School. His research focuses on cancer metabolism, including the signaling basis underlying cancer metabolism and nutritional influences on cancer and responses to therapy. Key publications include “Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity” (Nature, 2023), “Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation” (Molecular Cell, 2022), and “Prevention of Dietary-Fat-Fueled Ketogenesis Attenuates BRAF V600E Tumor Growth” (Cell Metabolism, 2017). Among his honors are the Leukemia and Lymphoma Society Career Development Program Scholar Award, American Cancer Society Basic Research Scholar Award, and Winship Cancer Institute awards.
University of Chicago study reveals zeaxanthin enhances CD8+ T cells, boosting immunotherapy efficacy in cancer models. Explore mechanism, sources, trials.