Michel L. Tremblay is the Distinguished James McGill Professor in the Department of Biochemistry at McGill University, with additional appointments in the Departments of Oncology and Microbiology and Immunology in the Faculty of Medicine and Health Sciences. He is also affiliated with the Rosalind and Morris Goodman Cancer Institute. He earned his Ph.D. from McMaster University in 1988 and completed postdoctoral training at the National Institutes of Health. He joined McGill University in 1992 as an assistant professor in the Department of Biochemistry.
His research focuses on the role and function of protein tyrosine phosphatases (PTPases) in cellular signaling pathways implicated in cancer, the immune system, diabetes, obesity, and other conditions. The laboratory employs biochemical, genetic, and OMICs approaches, including the generation of knockout mouse models, to study specific PTPases such as PTP1B, TC-PTP, PTP-PEST, RPTP-sigma, and PRL-2. Tremblay has held appointments including James McGill Professor (2004–2010) and Jeanne and J.-Louis Levesque Chair in Cancer Research (from 2005). He is a Fellow of the Royal Society of Canada (elected 2006) and has received awards including the Robert L. Noble Award of the Canadian Cancer Society (2013), the McLaughlin Medal of the Royal Society of Canada (2017), and the title of Knight of the Ordre National du Québec (2015). He has authored or co-authored numerous publications on PTPases and their therapeutic potential.