Miriam Klein-Flügge is an Associate Professor in the Department of Experimental Psychology at the University of Oxford, with joint affiliation to the Department of Psychiatry and the Wellcome Centre for Integrative Neuroimaging. She serves as Principal Investigator of the Motivation, Decision and Neurostimulation (MoDeS) lab and is a Fellow at Corpus Christi College. She holds a Wellcome Trust/Royal Society Sir Henry Dale Fellowship and a UKRI/ERC Starting Grant. Klein-Flügge completed an undergraduate degree in Mathematics, Computer Science and Cognitive Science from the University of Osnabrück (Germany) and McGill University (Canada), an MSc in Neuroscience at the University of Oxford, and a PhD in Cognitive Neuroscience at UCL under the supervision of Sven Bestmann. Her postdoctoral research as a Sir Henry Wellcome Fellow was conducted in Matthew Rushworth’s laboratory at Oxford.
Her research examines processes related to emotion, motivation and decision-making, with a focus on how the human brain enables flexible adjustment of decisions to complex internal and external circumstances, including physical effort, sequences of actions and contextual changes. She employs brain imaging techniques such as fMRI, MEG and EEG, along with causal stimulation methods including TMS, tDCS and focused ultrasound, as well as computational modelling and behavioural tasks. Additional themes include the structure and function of subcortical regions and alterations in decision computations associated with mental illness. Klein-Flügge has received multiple fellowships and awards, including the Sir Henry Wellcome Postdoctoral Fellowship, a Wolfson College Junior Research Fellowship and an invitation to the Lindau Nobel Laureate Meeting. Key publications include work in Neuron (2022), Nature (2021), Nature Communications (various years) and other high-impact journals on topics such as effort-based decision-making, novel choice and amygdala connectivity. She contributes to public outreach activities focused on neuroscience education.