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Tomohisa Sujino is Associate Professor (Non-tenured) in the Sakaguchi Laboratory of the Department of Multidimensional Analysis of Gastrointestinal Biology at Keio University School of Medicine. His research aims to elucidate the pathogenesis of human gastrointestinal diseases using single-cell RNA-seq and spatial transcriptomics analysis as well as localization and kinetic analysis of immune cells at the single-cell level in the field of gastrointestinal immunology and endoscopy.
Sujino leads a laboratory focused on mucosal immunology, particularly how the gut microbiome and intestinal antigens influence the gut microenvironment and contribute to disease. He has published over 100 research papers on these topics, with Scopus data indicating 88 papers, 2093 citations, and an h-index of 23 as of mid-2026. Recent publications include studies on clinical outcomes after discontinuation of indigo naturalis in ulcerative colitis patients, characteristics of ulcerative colitis-associated neoplasia, video capsule endoscopy in obscure gastrointestinal bleeding, gastrointestinal symptoms in COVID-19, and downregulation of chemokine receptor 9 in intraepithelial lymphocyte development. Sujino participates in competitive research projects, delivers lectures at international and domestic conferences, and contributes to collaborative research efforts in gastrointestinal biology.
Keio University study uncovers how gut epithelial cells prime pathogenic Th17 cells causing MS neuroinflammation, opening new therapeutic paths.
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