Rate My Professor Vicky Maltby

Dr Maltby's research expertise is in Epigenetics and Medical Genetics, with fields of research allocated as 80% Epigenetics (including genome methylation and epigenomics), 10% Immunogenetics (including genetic immunology), and 10% Cognition. Her work examines epigenetic mechanisms underlying multiple sclerosis (MS), including genome-wide DNA methylation changes in CD19+ B cells from relapsing-remitting MS patients, increased DNA methylation of SLFN12 in CD4+ and CD8+ T cells from MS patients, epigenetic differences at the HTR2A locus in progressive MS patients, whole-blood methylation signatures associated with MS disease severity, and biological mechanisms of pregnancy's lasting effect on MS outcomes. Key publications include Jacobs BM, Vandebergh M, Maltby VE, Dobson R, Kreft KL, 'Interplay between genetic and environmental risk factors in multiple sclerosis: what have we learned?', Brain (2026); Maltby VE, Scott RJ, Giovannoni G, Hawkes CH, Levy M, Yeh EA, Lechner-Scott J, 'Where does multiple sclerosis come from?', Multiple Sclerosis and Related Disorders 85 (2024); Maltby VE et al., 'Efficacy of Cladribine Tablets as a Treatment for People With Multiple Sclerosis: Protocol for the CLOBAS Study', JMIR Research Protocols 10 (2021); Maltby VE et al., 'Genome-wide DNA methylation profiling of CD8+ T cells shows a distinct epigenetic signature to CD4+ T cells in multiple sclerosis patients', Clinical Epigenetics 7 (2015). Dr Maltby has authored 49 journal articles and delivered 55 conference presentations.