How do you decide when a cryo-EM structure is good enough to publish?
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I keep running into the same question when preparing a cryo-EM structure for submission: the map looks reasonable, but I'm never fully sure what resolution or validation standard reviewers will expect.
Different papers seem to apply different thresholds, and the field's guidance keeps shifting.
How do you decide when a structure is solid enough to submit, and what do you check before you do?