All Ranks: Assistant /Associate/ Professor of Neurology (Tenure or Tenure-Track)

Position Description

The Carol and Gene Ludwig Center at the Columbia University Irving Medical Center is seeking an investigator to join a team of clinician scientists, computational biologists, statistical geneticists, cell biologists, molecular biologists and protein chemists/biophysicists. The goal of the team is to understand the fundamental biology of neurodegenerative diseases, especially Alzheimer disease.

The successful candidate will bring complementary skills and interests that further enhance the capacity of the team to delve more deeply into disease pathobiology. Specifically, the successful candidate will apply their expertise to investigate the functional effects of genetic variants (or pools of genetic variants) that have been nominated by prior genetic studies (GWAS, WGS et cetera) and then further filtered/enriched by computational methods.

Other responsibilities include:

• Will collaboratively engage with existing expertise in clinical research (Neurology, neuropathology, neuropsychology), statistical genetics, computational biology, cellular biology (including spatial multi-omics) and biochemistry (protein biochemistry, metabolomics, lipidomics, neuro-inflammation);
• Will work especially closely with core faculty of the Carol and Gene Ludwig Center to generate ideas for new multi-PI collaborative efforts to uncover mechanisms leading to dysregulation and resilience in neurodegeneration
• Participate in the intellectual activities of the Carol and Gene Ludwig Center including participation in weekly lab meetings with other labs, monthly Ludwig Scholar’s and Taub Institute seminars and annual symposia,
• Participate in/peer review Ludwig pilot grant program.
• Grow their own research program through internal and external grant applications, and through the hiring and supervision of their own lab staff;
• Apply for research grants to support their salary, staff’s salary and equipment/consumables.
• Supervise and mentor of undergraduate, graduate, postgraduate and postdoctoral learners (and as appropriate, other faculty).

About The Carol and Gene Ludwig Center for Research on Neurodegeneration

The Carol and Gene Ludwig Center for Research on Neurodegeneration (CGLC) was established in 2022 and is located in the heart of the Columbia University Irving Medical Center within the Department of Neurology.

Qualifications

Requirements & Qualifications:

• PhD, MD PhD, or MD degree;
• Completed postdoctoral training in an area of molecular biology, cell biology, biophysics, bioengineering in the general areas of functional genomics, fundamental neurobiology or translational neurobiology;
• Track record of publication of impactful peer-reviewed research papers (career stage dependent);
• Track record of successful acquisition of Peer-reviewed grants (career stage dependent);
• Track record of productive collaborative work in multidisciplinary team settings;
• Demonstration of original (“out-of-the-box”) thinking on research topics.
• Demonstration of resilience, curiosity, innovation and receptiveness to experimental risk-taking to pursue new ideas.