metabolic intervention can prevent arthritis-associated cardiovascular damage.
The doctoral candidate will:
- Define temporal changes in cardiac macrophage, fibroblast and endothelial-cell states during inflammatory arthritis and evolving cardiac dysfunction.
- Establish how mitochondrial function, oxidative stress and metabolic rewiring shape cardiac inflammation and tissue remodelling.
- Test whether targeted metabolic and pro-resolving interventions can protect the heart while controlling joint inflammation.
Training and research environment
Experimental arthritis and cardiovascular models; echocardiography; cardiac immunology; multiparameter flow cytometry; mitochondrial and oxidative-stress assays; qPCR and RNA sequencing; metabolomics and lipidomics; and translational analysis of patient samples.
Candidate profile
A strong background in immunology, cardiovascular biology, pharmacology, metabolism or molecular medicine. Experience in cell biology, flow cytometry or experimental models is advantageous.
Candidates of any nationality are welcome to apply. Applicants should hold, or expect to obtain by October 2026, a Master’s degree (or equivalent qualification) that permits doctoral enrolment at QMUL. Applicants must not already hold a doctoral degree, must be proficient in English, and must satisfy the MSCA mobility rule: they must not have resided or carried out their principal activity in the United Kingdom for more than 12 months in the 36 months immediately preceding recruitment.
Application information
For more information, please visit: https://harpnet.eu/recruitment/
For any queries related to the applications please contact: info@harpnet.eu
Funding Notes
This is a fully funded Doctoral Candidate position within HARPNET, a Marie Skłodowska-Curie Actions Doctoral Network. HARPNET brings together universities, hospitals and industry partners across Europe to advance Resolution Pharmacology: the science of actively switching off harmful inflammation and promoting tissue repair. The doctoral candidate will join an international cohort of 15 researchers and undertake interdisciplinary training, network activities and international secondments.
The funding includes an employment contract and the applicable MSCA living and mobility allowances; family allowances may apply where eligible. Candidates should submit one central HARPNET application and may rank up to three project choices.
