Job Information
Organisation/Company: InLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences
Research Field: Biological sciences » Biology; Biological sciences » Other; Technology » Biotechnology
Researcher Profile: First Stage Researcher (R1)
Positions: Master Positions
Application Deadline: 13 Sep 2026 - 23:59 (Europe/Warsaw)
Country: Poland
Type of Contract: Not Applicable
Job Status: Full-time
Hours Per Week: 40
Offer Starting Date: 1 Oct 2026
Is the job funded through the EU Research Framework Programme?: Not funded by a EU programme
Is the Job related to staff position within a Research Infrastructure?: No
Offer Description
Title of the project: CHRONOFLOW: Integrated circadian transcriptomic, microRNA, and proteomic profiling of the choroid plexus in relation to blood-cerebrospinal fluid barrier function and glymphatic rhythmicity
Competition: OPUS 29
PI: dr Aleksandra Szczepkowska
Project Information:
Why does the brain clear waste more efficiently during sleep? How do biological rhythms influence brain homeostasis?
CHRONOFLOW explores these questions by investigating one of the brain's most overlooked yet essential structures, the choroid plexus, which produces cerebrospinal fluid (CSF) and forms the blood-CSF barrier. Although the choroid plexus is essential for normal brain function, many of the molecular mechanisms regulating its circadian activity remain unknown. The project combines animal models, cell culture, advanced molecular profiling, functional assays and computational data analysis to investigate the biological mechanisms underlying circadian regulation of the choroid plexus and glymphatic system.
Joining CHRONOFLOW offers the opportunity to work with cutting-edge experimental approaches and to develop interdisciplinary expertise at the interface of neuroscience, chronobiology, molecular biology and bioinformatics.
The successful candidate will be responsible for:
- Participation in animal experiments conducted across the 24-hour circadian cycle;
- Isolation of the choroid plexus and cerebral cortex, tissue verification, and downstream sample processing;
- Performing molecular biology analyses, including RNA and protein isolation, quality and quantity assessment, reverse transcription, and real-time PCR;
- Statistical analysis of circadian rhythmicity in experimental data;
- Fluorescence-based assays;
- In vitro barriers studies;
- Collection, analysis and interpretation of experimental data;
- Preparation of scientific manuscripts and a doctoral dissertation in the form of a PhD by publication;
Important: The project involves regular work with laboratory rodents (Wistar rats), including habituation and handling procedures designed to minimize animal stress before experimental procedures, as well as collecting tissues and biological samples for research purposes. Candidates are encouraged to carefully consider whether they are comfortable working directly with laboratory animals and animal-derived biological material before applying.
Where to apply
Website: https://sd.pan.olsztyn.pl/en/application-form/
Requirements
Research Field: Biological sciences » Biology; Biological sciences » Other; Technology » Biotechnology
Education Level: Master Degree or equivalent
Skills/Qualifications
Requirements:
- Education requirements: Master's degree in biology, biotechnology or a related field (master's degree obtained before the project start - 1 October 2026);
- Basic understanding of animal physiology;
- No contraindications to working with laboratory animals and biological material;
- Basic knowledge of molecular biology, biochemical assays, cell culture techniques, and statistical data analysis;
- Very good command of spoken and written English;
- Strong motivation for scientific research, analytical thinking, the ability to critically analyze scientific literature, good organizational skills, and the ability to work both independently and as part of a team.
Additional assets:
- Previous experience with in vivo and/or in vitro experiments is welcome;
- Interest in neuroscience, chronobiology, neuroimmunology, or brain barrier research;
- Practical experience in molecular biology techniques;
- Basic knowledge of statistical analysis;
- Research internships, membership in scientific societies or student research clubs, conference participation, and other scientific achievements considered relevant by the candidate will be regarded as an advantage.
Languages: ENGLISH — Level: Excellent
Additional Information
Benefits
- Application submission period: September 13, 2026 (until 23:59 CEST)
- Application method: application form
- Interviews: September 18 - 23, 2026 (via Zoom)
- Location: Olsztyn, Poland
- Duration of the scholarship: 48 months
- Expected start date: October 1st, 2026
- Number of positions: 1
Eligibility criteria
- Relevant Master's Degree Diploma obtainted before 1st October, 2026;
- Complete documentation required in the Application Form;
- Application before the deadline.
Selection process
- September 13, 2026 (until 23:59 CEST)
- Applications will be assessed in accordance with the criteria set out in the regulations for awarding research scholarships in research projects financed by the National Science Centre;
- Only online applications will be considered;
- Candidates evaluated with the highest score will be invited to an actual interview, which will take place face-to-face or online;
- During the interview, the candidate will be asked to deliver a 10-minute presentation on their Master's thesis and research interests;
- The final recruitment results will be published on InLife webpage within 10 days after final decision.
Website for additional job details: https://sd.pan.olsztyn.pl/en/recruitment/recruitment-2026-2027/
Work Location(s)
Number of offers available: 1
Company/Institute: InLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences
Country: Poland
City: Olsztyn
Postal Code: 10-683
Street: ul. Trylińskiego 18
Contact
State/Province: Warmian-Masurian Province
City: Olsztyn
Website: http://www.pan.olsztyn.pl
Street: Władysława Trylińskiego 18
Postal Code: 10-683
E-Mail: s.zielinski@pan.olsztyn.pl; a.sikorska@pan.olsztyn.pl
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