Left–right asymmetry (chirality) in land snails has long served as a model for understanding developmental evolution, but on São Tomé and Príncipe it intersects with an urgent conservation challenge. These tropical island islands are home to Archachatina bicarinata, a giant left-coiling snail now endangered and declining, as well as multiple other left-coiling snail species. Unfortunately, emerging evidence suggests that a related snail, A. marginata, introduced because it is edible, may spread…
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