Grading of vitreous degeneration by IRcSLO imaging

About the Project

Imaging of the vitreous in the human eye is often carried out by optical coherence tomography (OCT). However, OCT images are static and provide information about backscattering of scattering centres within the vitreous body. Forward scattering effects are considerably greater than backscattering and are important as they are the effects witnessed by the patient with vitreous degeneration. Infra-Red confocal Scanning Laser Ophthalmoscopy (IRcSLO) is a technique which can provide dynamic information on forward scattering by scattering centres within the vitreous and is thus a more useful tool in the diagnosis and estimation of severity of vitreous degeneration. The research project proposes application of suitable Image processing techniques to enable the removal of intensity changes on the retina caused by mobile scattering centres in the vitreous body from the fixed anatomy of the eye. This separation can then be used to estimate mobility and severity vitreous degeneration, providing an objective grading system for clinical use.

Funding Notes

there is no funding for this project

References

Harmer, S. W., Luff, A. J., & Gini, G. (2022). Optical Scattering from Vitreous Floaters. Bioelectromagnetics, 43(2), 90–105. https://doi.org/10.1002/bem.22386