About the Project
The McDole lab seeks to understand how complex 3D structures in the embryo are sculpted from initially homogenous cell populations. For example, how does an intricate, functional organ such as a beating heart arise from a uniform ball of cells? How do tubes involute and tissues fold, and what are the physical forces that drive these shape changes? Furthermore, how do cells themselves cope with different and changing mechanical environments, and how does this affect their gene expression and…
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