"Investigating the antigenic specific CD8⁺ T cell response and its change with aging"

We are recruiting goal-oriented, creative, and highly motivated postdoctoral fellows to apply single-cell omics approaches: including transcriptomics, TCR repertoire analysis, epigenomics, and somatic mutation profiling, to study the mechanisms of CD8⁺ T cell differentiation, immune responses, and their changes with age. Our research focuses on defining the transcriptomic and TCR repertoire features of CD8⁺ T cell responses to viral antigens, including SARS-CoV-2, influenza A virus (IAV), and cytomegalovirus (CMV), and how these responses change with aging. We use both human samples and mouse models to address fundamental questions in T cell immunity and to advance translational applications in medicine. We encourage applicants with backgrounds in immunology, microbiology, genetics, cell biology, molecular biology, or bioengineering to apply. Successful candidates should hold a PhD or MD/PhD and have strong research experience. Prior experience in molecular biology, immunology, and working with human and/or mouse models is preferred. To apply, applicants should send their Curriculum Vitae, a description of past research accomplishments, future research interests, and three names for reference to:

Dr. Nan-ping Weng

Laboratory of Molecular Biology and Immunology

National Institute on Aging, NIH

251 Bayview Blvd. Suite 100

Baltimore, MD 21224

Email: wengn@mail.nih.gov