Medical Research Tech IV

Employees in this classification provide support in an assigned research laboratory conducting specified phases of research projects. Performs work independently and responsible for developing new procedures and techniques to be utilized in the laboratory research projects. Performs work independently and responsible for developing new procedures and techniques to be utilized in the laboratory and in experiments, and new applications for standard procedures and techniques. Work is performed under usual laboratory conditions. Some hazards maybe present due to use of radioactive, carcinogenic or other potentially harmful substances. Responsibilities include ensuring overall cleanliness of the laboratory and equipment, and for ordering and maintaining an adequate stock of necessary supplies. May instruct or direct work of subordinate laboratory personnel.

Major/Essential Functions

• Testing the central hypothesis that Ubiquitin C-terminal Hydrolase L1 (UCHL1) is a driver of vascular and neurobehavioral function through mechanisms of glycosaminoglycan sulfation and accumulation associated with repetitive mild traumatic brain injury.
• Oversight and coordination of the UCHL1 mouse colony; coordination of breeding, genotyping, specimen labeling, and keeping other lab members abreast of mouse availability and helping to plan experiments.
• Serving as a user for liquid chromatography mass spectrometry, cryostat and confocal microscopy equipment.
• Laboratory administration (Following standard operating procedures, lab safety, protocol creation/maintenance, orderliness and reporting); provide logistical support for graduate student scientists and other lab personnel

Preferred Qualifications

• Experience with Animal handling is preferred.
• Prior knowledge in leading behavioral experiments, cryostat sectioning of brain tissue, mouse colony maintenance, genotyping, histology/analytical workflows, and accompanying analyses.

Required Qualifications

Master's degree in one of the sciences, or equivalent combination (6 years) of job-related experience and college education. Experience may be substituted for college education on a year for year basis.