This exciting PhD project will investigate how cancer cells alter their metabolism to escape programmed cell death and continue growing. Understanding these mechanisms could reveal new ways to treat cancer by targeting the pathways that help tumour cells survive.

Our group, in collaboration with Dr Concetta Bubici at Brunel University of London, has conducted a series of interdisciplinary studies to investigate the intracellular mechanisms regulating cell survival. In this project, we will investigate the intracellular pathways regulating the metabolic reprogramming in normal and disease conditions using cell-based techniques and in-vivo models of disease. Working within an established, internationally collaborative research team, you will explore how specific genes control cell survival and metabolism in a range of cancers, including liver cancer, breast cancer, lymphoma, and myeloma. Using a combination of cell biology, mouse genetics, and metabolic analyses, you will study how these pathways influence cancer development, treatment resistance, and tissue regeneration.

This exciting PhD project will investigate how cancer cells alter their metabolism to escape programmed cell death and continue growing. Understanding these mechanisms could reveal new ways to treat cancer by targeting the pathways that help tumour cells survive.

Our group, in collaboration with Dr Concetta Bubici at Brunel University of London, has conducted a series of interdisciplinary studies to investigate the intracellular mechanisms regulating cell survival. In this project, we will investigate the intracellular pathways regulating the metabolic reprogramming in normal and disease conditions using cell-based techniques and in-vivo models of disease. Working within an established, internationally collaborative research team, you will explore how specific genes control cell survival and metabolism in a range of cancers, including liver cancer, breast cancer, lymphoma, and myeloma. Using a combination of cell biology, mouse genetics, and metabolic analyses, you will study how these pathways influence cancer development, treatment resistance, and tissue regeneration.