About the project
Biomolecular condensates are crucial organisers of cellular biochemistry and hence physiology. The paraspeckle is a stress-responsive nuclear condensate dysregulated in human diseases such as cancer, neurodegeneration and infectious diseases. In contrast to most phase-separated assemblies, paraspeckles are highly ordered, with their size and structure dictated by the properties of the scaffolding RNA molecule. Paraspeckles represent a unique model system for the studies of condensate assembly…
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