PhD student position in innate immunology / immune imaging in the Dudeck Lab

About the Project

The DUDECK LAB (Research Group IMMUNOREGULATION) at the INSTITUTE FOR CLINICAL IMMUNOLOGY AND CELL THERAPEUTICA, OTTO-VON-GUERICKE UNIVERSITY MAGDEBURG,

is looking for highly motivated early-career researchers

We offer a PhD Student position (salary according to german TVL E13, 65%), initially limited to 3 years

Our research focus

We investigate the functional relevance of mast cells in innate and adaptive immune responses, as well as in acute and chronic inflammatory processes, in vivo. Our research focuses on the intercellular communication of mast cells with tissue-resident immune cells, such as dendritic cells and macrophages, as well as non-immune cells, including the endothelium and epithelium. We also examine the characteristics of perivascular mast cells and their influence on blood vessel activation and the recruitment of effector immune cells. Of further interest are the functions of mast cells in regulating barrier integrity and inter-organ communication. To this end, we use innovative transgenic in vivo mouse models and combine high-end imaging techniques, such as intravital two-photon microscopy, three-dimensional light-sheet microscopy, multi-parameter microscopy and live-cell imaging, with molecular biology, cell biology, immunology methods and omics technologies.

(current publications and ongoing research projects can be found at https://www.dudeck-lab.de https://imki.med.ovgu.de/Forschung/Forschungsgruppen/AG+Dudeck.html)

Your profile

We are looking for highly self-motivated candidates with a very good background in biology, biochemistry or related disciplines, keen interest in immunology/allergy/inflammation research and very good teamwork skills to join our research-oriented, ambitious and international team. Experience in cell biological, immunological or molecular biological methods is required. Experience in working with transgenic mouse models and corresponding qualifications, tissue processing or microscopy techniques are advantageous.

We offer

A multifaceted, exciting position in a highly motivated and internationally visible research team in the field of mast cell biology, and using innovative techniques. Our unique selling point is the imaging-based monitoring of intercellular communication in the context of inflammatory processes. Our group is part of the well-equipped Institute for Clinical Immunology and Cell Therapeutics, and innovative imaging techniques are available at the Multiparametric Bioimaging and Cytometry platfrom. Applicants can be associated with the RTG2408 graduate school (“Maladaptive processes across physiological barriers in chronic diseases”) to benefit from close networking with other PhD students and to participate in the supervised qualification programs (for more information see http://grk2408.ovgu.de/)

If you have any questions, please contact Prof. Dr. Anne Dudeck (Tel. +49-391-67-15382, e-mail: anne.dudeck@med.ovgu.de), Institute for Clinical Immunology and Cell Therapeutics, Otto-von-Guericke University Magdeburg.

Please send your application (including motivation letter, CV, and contact details of a referee) summarized as a single PDF file by May 15th 2026 by e-mail to: anne.dudeck@med.ovgu.de.

Funding Notes

project funded by the German Research Foundation (Deutsche Forschungsgemeinsch(DFG))