Position Overview

The Fan Laboratory in the Department of Radiation Oncology at the University of Pennsylvania’s Perelman School of Medicine is recruiting creative, collaborative, and highly motivated Postdoctoral Scientists to lead research projects in cancer immunology and cardiovascular biology.

Research Focus

The lab investigates how the tissue microenvironment regulates cancer immunity and heart repair.

Key areas of interest include:

Molecular mechanisms underlying vascular control of immune cell function in cancer and ischemic heart disease
Targeting myeloid cells to overcome cancer-associated immunosuppression
Biology and therapeutic targeting of γδT cell and NKT cell exhaustion in cancer
Advanced radiation strategies, including FLASH and SFRT, to modulate tissue immunity in tumors and normal hearts

Research Approach

The research integrates:

Mouse models
Molecular and cell biology
Immunology and metabolism
Multi-omics approaches (transcriptomics, epigenomics, proteomics)
Advanced 3D imaging

The goal is to uncover molecular pathways and develop novel therapeutic strategies.

Project Areas

Projects will be tailored to candidate interests within themes such as:

Molecular communication among endothelial cells, fibroblasts, macrophages, and dendritic cells
Metabolic and transcriptional mechanisms regulating γδT cell dysfunction in the tumor microenvironment
Combinatorial strategies integrating CAR-T cell therapy with FLASH- and SFRT-based radiotherapy
Targeting endothelial plasticity and myeloid cell transitions to improve cardiac repair following ischemia

Lab Environment

The Fan Lab emphasizes:

Rigorous science
Intellectual independence
Strong mentorship

The lab has a strong track record of training researchers who advance to independent faculty positions.

Required Qualifications

PhD in Cancer Biology, Immunology, Cell Biology, or related field
Demonstrated research productivity (including first-author publications)
Strong experimental and analytical skills in molecular, cellular, or tissue biology
Ability to independently design and execute experiments

Preferred Qualifications

Experience with mouse models
Background in metabolism and/or immunological analysis
Experience in cancer and/or cardiovascular research workflows
Bioinformatics skills (e.g., R, Python, or related tools)

Visa Information

Candidates requiring visa sponsorship are welcome to apply.

Application Instructions

Applicants should submit:

Curriculum vitae (CV)
Cover letter describing research experience and interests
PDF of relevant publication(s)
Contact information for three references

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Postdoctoral Fellow in Oncology

University of Pennsylvania Perelman School of Medicine

3400 Civic Center Blvd, Philadelphia, PA 19104, USA

Position Overview

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University of Pennsylvania Perelman School of Medicine

3400 Civic Center Blvd, Philadelphia, PA 19104, USA

Position Overview

This is a Preview Listing…

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Postdoctoral Fellow in Oncology

University of Pennsylvania Perelman School of Medicine

3400 Civic Center Blvd, Philadelphia, PA 19104, USA

Position Overview

This is a Preview Listing…

Related Jobs

Related Research Grants

Grants to USA Entities for Resource Management Research

Grants to USA Entities for Research on Engineering Systems

Grants to USA Entities for Advanced Materials Research

Grants to USA Entities for Intelligent Dynamic Systems Research

Grants to USA Entities for Civil Infrastructure Research

Grants to USA Entities for Nanochemistry, Supramolecular, and Macromolecular Chemistry Research

Grants to USA IHEs, Nonprofits, and Tribes for Chemistry Research on Life Processes

Grants to USA Entities for Chemical Computational Methods, Models, and Theory Research

Related Conferences

2026 AAA Annual Meeting: On the Verge

87th Annual Meeting of the Society for Applied Anthropology

AABA Annual Meeting 2027

75th Annual Highway Geology Symposium

GSA Annual Meeting 2026

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APS Division of Nuclear Physics Meeting (DNP 2026)

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Postdoctoral Fellow in Oncology

University of Pennsylvania Perelman School of Medicine