Postdoctoral Fellow in Pediatrics

Appointment Type

Postdoctoral Fellow

Department

IUSM - Pediatrics

Position Summary

The Schwaderer Lab is dedicated to uncovering the biological mechanisms underlying kidney diseases, particularly those with immune-mediated components such as kidney infections, kidney stones, and glomerular disorders. Our research integrates cutting-edge approaches to understand how immune responses contribute to kidney injury and disease progression. In addition, we focus on biomarker discovery to identify children at risk for developing kidney disease and to guide personalized treatment strategies. By leveraging advanced technologies in genomics, proteomics, and metabolomics, our goal is to improve early detection, predict disease outcomes, and develop targeted interventions that enhance patient care and long-term kidney health.

Bioinformatics and Biomarker Analysis in Kidney Disease

The Nephrology and Urology Research Group at Indiana University School of Medicine seeks a highly motivated individual to join our team in advancing the understanding of kidney disease through cutting-edge bioinformatics and biomarker research. This position focuses on the integration and analysis of complex biological data to identify and validate kidney disease biomarkers.

Research Focus

Our program leverages multi-omics platforms (including proteomics, metabolomics, transcriptomics), targeted biomarker arrays, and advanced computational approaches to: Characterize biomarker profiles across kidney tissue, serum, urine, and other biological samples. Integrate multi-modal datasets to uncover mechanisms underlying kidney disease progression and treatment response. Apply advanced microscopy image analysis and spatial transcriptomics to link molecular signatures with tissue architecture. Develop predictive models for disease diagnosis, prognosis, and therapeutic targeting.

Experimental and Analytical Approaches

Bioinformatics and computational biology for multi-omics integration and biomarker discovery. High-dimensional data analysis from targeted arrays and imaging platforms. Coordination of biological sample pipelines (kidney biopsy, serum, urine) for comprehensive biomarker profiling. Utilization of machine learning and image processing for advanced tissue analysis.

The Herman B Wells Center for Pediatric Research conducts basic science and translational research within the Department of Pediatrics at Indiana University School of Medicine. The Wells Center houses more than 300 faculty investigators, staff, and trainees seeking answers to the most pressing questions related to childhood illness. With the collaboration between scientists and physicians, the center aims to increase knowledge of causes and mechanisms of serious pediatric diseases. Our goal is to develop innovative approaches to the diagnosis and treatment of sick children in Indiana and beyond.

IUSM is committed to being a welcoming campus community and we seek candidates whose research, teaching, and community engagement efforts contribute to robust learning and working environments for all students, staff, and faculty. We invite individuals who will join us in our mission to improve health equity and well-being for all throughout the state of Indiana.