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Postdoctoral Research Associate in Molecular Mechanisms of Protein Complex Assembly

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University of Oxford

Department of Biochemistry, South Parks Road, Oxford, OX1 3QU

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Postdoctoral Research Associate in Molecular Mechanisms of Protein Complex Assembly

Grade 7

18 May 2026, 12:00 noon

Location

South Parks Road, Oxford, OX1 3QU

University of Oxford

Type

Full-time Fixed-term (up to 3 years)

Salary

£42,794 - £47,779 per annum

Required Qualifications

PhD/DPhil in Biochemistry, Cell Biology, Molecular Biology or related
Experience in cell biology and membrane trafficking
Strong analytical skills and research productivity
Yeast/mammalian genetics (advantage)
GTPase/Rab proteins experience (advantage)

Research Areas

Membrane protein homeostasis
Protein complex assembly/trafficking/degradation
Cell biology
Yeast genetics
Proteomics
Fluorescence microscopy
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Postdoctoral Research Associate in Molecular Mechanisms of Protein Complex Assembly

About the role

We are seeking a highly motivated Postdoctoral Research Associate to join the lab of Dr Haoxi Wu. This exciting opportunity focuses on carrying out research on a discrete area of a project investigating how multi-subunit membrane protein complexes are assembled, trafficked, and degraded, with the goal of uncovering fundamental principles governing membrane protein homeostasis and informing new avenues for therapeutic intervention.

Working under the supervision of Dr Haoxi Wu, you will lead experimental research investigating key aspects of membrane protein homeostasis. You will design and execute independent experiments using approaches including cell biology, fluorescence microscopy, yeast genetics, proteomics, flow cytometry, and in vitro biochemistry. You will contribute to high‑quality publications and present your work at scientific meetings, while also supporting and mentoring junior members of the research group.

This full-time fixed-term post is funded by the Wellcome Trust for up to 3 years in the first instance.

The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available.

About you

You will hold (or be near completion of) a PhD/DPhil in Biochemistry, Cell Biology, Molecular Biology or a related field, with experience in cell biology and membrane trafficking pathways. You will bring strong analytical skills, a track record of research productivity, and the ability to communicate your work clearly in writing and presentations. Experience with GTPase biology, Rab proteins, or genetic manipulation in yeast or mammalian systems, as well as mentoring junior researchers, would be an advantage.

What We Offer

Your happiness and wellbeing at work matters to us, so we offer a range of family-friendly and financial benefits including:

  • An excellent contributory pension scheme
  • 38 days annual leave
  • A comprehensive range of childcare services
  • Family leave schemes
  • Cycle loan scheme
  • Membership to a variety of social and sports clubs
  • Discounted bus travel and Season Ticket travel loans

The University also runs an enormous amount of social groups and sports clubs for those looking for more than just a great place to work.

Application Process

Applications for this vacancy are to be made online via www.recruit.ox.ac.uk and Vacancy ID 186182. You will be required to upload your curriculum vitae and a supporting statement, setting out how you meet the selection criteria for the post, using examples of your skills and experience. Click here for information and advice on writing an effective Supporting Statement. As part of your application, you will be asked to provide details of two referees and indicate whether we can contact them now.

For further details, please refer to the How to apply section of the job description. Any further enquires may be directed to recruitment@bioch.ox.ac.uk.

The closing date for applications is 12.00 noon on Monday 18th May 2026. Only applications received before this time can be considered. Interviews for shortlisted candidates to be held as soon as possible thereafter.

Committed to equality and valuing diversity

Location: Dorothy Crowfoot Hodgkin Building, Biochemistry Department, South Parks Road, Oxford, OX1 3QU

Pay Scale: STANDARD RESEARCH GRADE 7 Salary: £42,794 - £47,779 per annum

Contract type: Fixed Term Contract for up to 3 years Hours: Full Time (37.5 hours per week)

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Frequently Asked Questions

🎓What qualifications are required for this Postdoctoral Research Associate position?

You must hold (or be near completion of) a PhD/DPhil in Biochemistry, Cell Biology, Molecular Biology or related field, with hands-on experience in cell biology and membrane trafficking pathways. Strong analytical skills and a proven track record of research productivity are essential. Advantages include experience with GTPase biology, Rab proteins, yeast genetics, or mentoring. Check postdoc jobs for similar roles.

🔬What does the research involve in Dr Haoxi Wu's lab?

The project investigates molecular mechanisms of multi-subunit membrane protein complex assembly, trafficking, and degradation to uncover principles of membrane protein homeostasis. You will design experiments using cell biology, fluorescence microscopy, yeast genetics, proteomics, flow cytometry, and in vitro biochemistry. Explore research jobs for more opportunities.

📝How do I apply for this Oxford Biochemistry postdoc role?

Apply online via www.recruit.ox.ac.uk using Vacancy ID 186182. Upload your CV and a supporting statement addressing selection criteria. Provide two referees. Deadline: 12:00 noon, 18 May 2026. See postdoc success tips.

💰What is the salary, contract, and benefits for this position?

Salary: £42,794 - £47,779 per annum (Grade 7). Full-time fixed-term up to 3 years (37.5 hours/week), funded by Wellcome Trust. Benefits include excellent pension, 38 days leave, childcare, family leave, cycle loans, sports clubs. View university salaries.

🚀What support and career development opportunities are offered?

Lead experiments, contribute to high-impact publications, present at meetings, and mentor juniors. Location: Dorothy Crowfoot Hodgkin Building, Oxford. University offers social/sports clubs. Ideal for advancing in academic research careers; see faculty jobs next steps.

🧪Is experience with specific techniques advantageous?

Yes, prior work with genetic manipulation in yeast or mammalian systems, GTPase/Rab biology, or mentoring is advantageous. Core skills: proteomics, flow cytometry. Aligns with research assistant excellence.
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