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Postdoctoral Research Associate in Ubiquitin E2 Mechanisms

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University of Oxford

Department of Biochemistry, South Parks Road, Oxford, OX1 3QU

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Postdoctoral Research Associate in Ubiquitin E2 Mechanisms

STANDARD RESEARCH GRADE 7

18 May 2026, 12:00 noon

Location

South Parks Road, Oxford, OX1 3QU

University of Oxford

Type

Full-time Fixed-term (up to 12 months)

Salary

£42,794 - £47,779 per annum

Required Qualifications

PhD/DPhil or near completion
Protein expression & purification
Ubiquitin system knowledge
In vitro ubiquitination assays
Structural biology (X-ray, NMR, cryoEM)
Small-molecule screening assays
Biophysical techniques (protein-protein/ligand interactions)

Research Areas

Ubiquitin E2 Mechanisms
Cell death regulation
Ubiquitin ligases
Protein biochemistry
Structural biology
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Postdoctoral Research Associate in Ubiquitin E2 Mechanisms

Location

Dorothy Crowfoot Hodgkin Building, Biochemistry Department, South Parks Road, Oxford, OX1 3QU

Pay Scale

STANDARD RESEARCH GRADE 7

Salary

£42,794 - £47,779 per annum

Location

Department of Biochemistry, South Parks Road, Oxford

Contract type

Fixed Term Contract for up to 12 months in the first instance

Hours

Full Time (37.5 hours per week)

About the role

The post holder will be a member of a dynamic and growing research group under the supervision of Associate Professor Paul Elliott in the Department of Biochemistry, University of Oxford. The postholder will be responsible for managing an independent project investigating the mechanisms of cell death, specifically the activity and regulation of several ubiquitin ligases, using a combination of protein biochemistry, biochemical, biophysical and structural biology assays. The post holder is expected to provide guidance and support within the research group to fellow postdocs, DPhil students and undergraduate project students, maintaining a strong collegiate environment.

This full-time fixed-term post is funded by the Cancer Research UK for up to 12 months in the first instance.

The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available.

About you

You will hold or be near completion of a PhD/DPhil and have a strong background in protein expression and purification techniques, with a good understanding of the ubiquitin system. You should have experience using in vitro ubiquitination assays and have a strong background in structural biology: X-ray, NMR or cryoEM. You will have proven experience of developing small-molecule screening assays and a background in biophysical techniques for measuring protein-protein and/or protein-ligand interactions. Excellent written and oral communication skills, with the ability to work with colleagues and students is essential.

What We Offer

  • An excellent contributory pension scheme
  • 38 days annual leave
  • A comprehensive range of childcare services
  • Family leave schemes
  • Cycle loan scheme
  • Membership to a variety of social and sports clubs
  • Discounted bus travel and Season Ticket travel loans

The University also runs an enormous amount of social groups and sports clubs for those looking for more than just a great place to work.

Application Process

Applications for this vacancy are to be made online via www.recruit.ox.ac.uk and Vacancy ID 186164. You will be required to upload your curriculum vitae and a supporting statement, setting out how you meet the selection criteria for the post, using examples of your skills and experience. Click here for information and advice on writing an effective Supporting Statement. As part of your application, you will be asked to provide details of two referees and indicate whether we can contact them now.

For further details, please refer to the How to apply section of the job description. Any further enquires may be directed to recruitment@bioch.ox.ac.uk.

The closing date for applications is 12.00 noon on Monday 18th May 2026. Only applications received before this time can be considered. Interviews for shortlisted candidates to be held as soon as possible thereafter.

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Frequently Asked Questions

🎓What qualifications are required for this Postdoctoral Research Associate role?

You must hold or be near completion of a PhD/DPhil with a strong background in protein expression and purification, the ubiquitin system, in vitro ubiquitination assays, and structural biology (X-ray, NMR, or cryoEM). Experience in small-molecule screening assays and biophysical techniques for protein interactions is essential, along with excellent communication skills. Check postdoc positions for similar requirements.

🔬What does the role involve in ubiquitin E2 mechanisms research?

The postholder will manage an independent project on cell death mechanisms, focusing on the activity and regulation of ubiquitin ligases using protein biochemistry, biophysical, and structural biology assays. You will provide guidance to postdocs, DPhil students, and undergraduates in a collegiate environment. Explore research jobs for more opportunities.

📅What is the salary, contract, and application deadline?

Salary is £42,794 - £47,779 per annum (Grade 7). This is a full-time fixed-term contract for up to 12 months, funded by Cancer Research UK. Applications close at 12:00 noon on 18 May 2026. Apply via www.recruit.ox.ac.uk (Vacancy ID 186164) with CV and supporting statement.

📝How do I apply and what supporting documents are needed?

Apply online at www.recruit.ox.ac.uk (Vacancy ID 186164). Upload your CV and a supporting statement addressing selection criteria with examples. Provide two referees. See postdoctoral success tips and free resume template for guidance.

🏥What benefits does University of Oxford offer?

Benefits include an excellent pension scheme, 38 days annual leave, childcare services, family leave, cycle loan, social/sports clubs, and discounted travel. The University fosters a vibrant community. View more at higher ed jobs.

📍Where is the position located and who is the supervisor?

Located at Dorothy Crowfoot Hodgkin Building, Department of Biochemistry, South Parks Road, Oxford, OX1 3QU. Supervised by Associate Professor Paul Elliott in a dynamic research group. Learn about thriving in postdoc roles.
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