Research Assistant in Mass Spectrometry based Metabolomics for in Situ Seeded Aggregation of Alpha-synuclein

Research Assistant in Mass Spectrometry based Metabolomics for in Situ Seeded Aggregation of Alpha-synuclein

The University of Manchester

Job reference: SAE-031673

Salary: £32,080 - £36,636 per annum depending on experience

Faculty/Organisational Unit: Science and Engineering

Location: Manchester Institute of Biotechnology

Employment type: Fixed Term

Division/Team: Department of Chemistry

Hours Per Week: Full Time (1 FTE)

Closing date (DD/MM/YYYY): 09/07/2026

Contract Duration: Fixed Term for 36 months

School/Directorate: School of Natural Sciences

We are seeking a motivated and collaborative individual to join our team as a Research Assistant in Mass Spectrometry‑based Metabolomics. This role offers an exciting opportunity to contribute to an ASAP‑funded international research project investigating seeded aggregation of alpha‑synuclein in Parkinson’s disease and related synucleinopathies. You will work within a dynamic and inclusive research environment at the Michael Barber Centre for Collaborative Mass Spectrometry, part of the Manchester Institute of Biotechnology.

This is a full‑time, fixed‑term role for 36 months, starting as soon as possible and running until 31st May 2029 (unless extended).

You will be responsible for:

• Supporting receipt, logging, storage and tracking of biological samples
• Preparing biological samples for mass spectrometry‑based metabolomics and lipidomics analysis
• Assisting with LC‑MS, MS/MS and ion‑mobility mass spectrometry workflows under supervision
• Operating, monitoring and maintaining mass spectrometry and chromatography equipment appropriate to training level
• Maintaining accurate laboratory records, data organisation and quality control documentation

We welcome candidates who bring diverse perspectives, experiences, and approaches to their work.

About you

We encourage applications from individuals with a wide range of backgrounds and experiences. You should demonstrate:

Essential criteria:

• A degree, or equivalent experience, in chemistry, analytical chemistry, biochemistry, biomedical science or a related discipline
• Practical laboratory experience in analytical science or biological sample preparation
• Experience of mass spectrometry, chromatography or related analytical techniques
• Strong organisational skills with excellent attention to detail and record‑keeping
• Ability to work effectively and reliably as part of a collaborative research team

Desirable criteria:

• Experience with LC‑MS, GC‑MS, ion mobility MS or tandem MS
• Experience preparing samples for metabolomics or lipidomics analysis
• Experience working with limited or precious biological material
• Experience working in a shared instrumentation facility or multidisciplinary environment
• Interest in neurodegeneration, Parkinson’s disease or biomedical mass spectrometry

We value reliability, care in laboratory practice and willingness to learn as much as formal experience.

Our benefits include:

• Generous employer pension contribution
• Christmas closure in addition to annual leave and bank holidays
• Purple Place employee discount platform

For more information, please see: www.manchester.ac.uk/connect/jobs/benefits-working-here.