Research Assistant - Induced Pluripotent Stem Cell (iPSC) Biobank
Job Description
We are seeking a highly motivated and detail-oriented Research Assistant to join our team at the forefront of iPSC biobanking and automation. The successful candidate will play a pivotal role not only in establishing automation workflow but also in the collection, characterization, and maintenance of induced pluripotent stem cell lines, contributing directly to cutting-edge research initiatives in regenerative medicine, disease modeling, and drug discovery.
Responsibilities:
- Automation specialist
- Develop, optimize and troubleshoot automated liquid handling protocols on the Opentrons platform.
- Designated person in charge of matters for the Opentrons system (assist with creating protocols if required for users interested in using the Opentrons for experiments)
- iPSC Culture and Maintenance:
- Execute established protocols for the culture and expansion of iPSC lines.
- Monitor cell growth, viability, and quality control parameters.
- Perform routine passaging and cryopreservation of iPSCs.
- Maintain accurate records of cell culture activities.
- iPSC Characterization:
- Conduct immunocytochemistry, flow cytometry, and molecular biology techniques to assess pluripotency and differentiation potential of iPSC lines.
- Perform karyotyping and other cytogenetic analyses to ensure genomic stability.
- Collaborate with researchers to design and implement experiments for iPSC characterization.
- Biobanking Operations:
- Coordinate sample collection, processing, and storage according to standardized protocols.
- Label, track, and catalog iPSC samples in the biobank database.
- Implement quality control measures to ensure sample integrity and compliance with regulatory requirements.
- Assist in the development and optimization of biobanking workflows.
- Data Management and Analysis:
- Compile and organize experimental data, including cell culture records, characterization results, and biobank inventory information.
- Analyze data using statistical methods and assist in the preparation of research reports and presentations.
- Contribute to the maintenance and updating of laboratory databases and electronic notebooks.
- Laboratory Support:
- Maintain cleanliness and orderliness of the laboratory.
- Assist in the procurement and organization of laboratory supplies and reagents.
- Support other members of the research team in experimental procedures and technical troubleshooting.
Qualifications
- Bachelor's in Biology, Biochemistry, Molecular Biology, or a related field.
- Experience with Python programming (particularly for scientific research)
- Hands-on experience in cell culture techniques, preferably with human pluripotent stem cells.
- Familiarity with basic molecular biology and cell biology techniques (e.g., PCR, Western blotting, immunocytochemistry).
- Strong organizational skills and attention to detail.
- Ability to work independently as well as part of a collaborative research team.
- Prior experience in biobanking or sample management is advantageous.
- Knowledge of relevant safety protocols and regulatory guidelines in cell culture and biobanking is desirable.
This position offers an exciting opportunity to contribute to gro
University-Level Unit: Yong Loo Lin School of Medicine
Faculty/Department-Level Unit: Medicine
Employee Category: Research Staff
Location: Kent Ridge Campus
Posting Start Date: 26/03/2026
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