Research Assistant - Induced Pluripotent Stem Cell (iPSC) Biobank

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Job Description

We are seeking a highly motivated and detail-oriented Research Assistant to join our team at the forefront of iPSC biobanking and automation. The successful candidate will play a pivotal role not only in establishing automation workflow but also in the collection, characterization, and maintenance of induced pluripotent stem cell lines, contributing directly to cutting-edge research initiatives in regenerative medicine, disease modeling, and drug discovery.

Responsibilities:

1. Automation specialist
   • Develop, optimize and troubleshoot automated liquid handling protocols on the Opentrons platform.
   • Designated person in charge of matters for the Opentrons system (assist with creating protocols if required for users interested in using the Opentrons for experiments)
2. iPSC Culture and Maintenance:
   • Execute established protocols for the culture and expansion of iPSC lines.
   • Monitor cell growth, viability, and quality control parameters.
   • Perform routine passaging and cryopreservation of iPSCs.
   • Maintain accurate records of cell culture activities.
3. iPSC Characterization:
   • Conduct immunocytochemistry, flow cytometry, and molecular biology techniques to assess pluripotency and differentiation potential of iPSC lines.
   • Perform karyotyping and other cytogenetic analyses to ensure genomic stability.
   • Collaborate with researchers to design and implement experiments for iPSC characterization.
4. Biobanking Operations:
   • Coordinate sample collection, processing, and storage according to standardized protocols.
   • Label, track, and catalog iPSC samples in the biobank database.
   • Implement quality control measures to ensure sample integrity and compliance with regulatory requirements.
   • Assist in the development and optimization of biobanking workflows.
5. Data Management and Analysis:
   • Compile and organize experimental data, including cell culture records, characterization results, and biobank inventory information.
   • Analyze data using statistical methods and assist in the preparation of research reports and presentations.
   • Contribute to the maintenance and updating of laboratory databases and electronic notebooks.
6. Laboratory Support:
   • Maintain cleanliness and orderliness of the laboratory.
   • Assist in the procurement and organization of laboratory supplies and reagents.
   • Support other members of the research team in experimental procedures and technical troubleshooting.

Qualifications

• Bachelor's in Biology, Biochemistry, Molecular Biology, or a related field.
• Experience with Python programming (particularly for scientific research)
• Hands-on experience in cell culture techniques, preferably with human pluripotent stem cells.
• Familiarity with basic molecular biology and cell biology techniques (e.g., PCR, Western blotting, immunocytochemistry).
• Strong organizational skills and attention to detail.
• Ability to work independently as well as part of a collaborative research team.
• Prior experience in biobanking or sample management is advantageous.
• Knowledge of relevant safety protocols and regulatory guidelines in cell culture and biobanking is desirable.

This position offers an exciting opportunity to contribute to gro

University-Level Unit: Yong Loo Lin School of Medicine

Faculty/Department-Level Unit: Medicine

Employee Category: Research Staff

Location: Kent Ridge Campus

Posting Start Date: 26/03/2026