Research Assistant | Laboratory of Molecular Biology

Organization Overview

The Heintz laboratory investigates the molecular logic that governs cellular function and dysfunction in the mammalian cerebrum. While classical neuroanatomy has defined the structural complexity of the brain with remarkable precision, the molecular mechanisms that orchestrate cell-to-cell interactions and maintain cerebral architecture remain incompletely understood. Our work focuses on uncovering these mechanisms at cell-type resolution, with a particular emphasis on how their disruption contributes to neurodegenerative disease. We integrate advanced genomic, epigenomic, and cell isolation approaches to study human brain tissue directly, enabling mechanistic insight into disorders such as Alzheimer’s and Huntington’s disease.

Overview

We are seeking a full-time Research Assistant to support a project on identifying novel strategies to delay onset and/or slow the progression of neurodegenerative diseases, such as Huntington's disease.

Responsibilities

Responsibilities include:

• Preparation of human brain samples for next generation sequencing
• Performing ATAC-seq, biulfite-seq, and Ox-bisulfite-seq assay
• Performing RNA extraction, cDNA preparation, PCR, gel electrophoresis, and library preparation

Qualifications

Required Qualifications:

• Bachelor of Science degree in Neuroscience, Biology, Psychology, or a related field
• Prior experience working in a research laboratory
• Strong organizational skills, attention to detail, and ability to maintain accurate records and follow standard operating procedures
• Excellent communication skills and the ability to work both independently and as part of a collaborative team in a fast-paced research environment

Preferred Qualifications:

• Master's degree with an educational emphasis in Neuroscience or Biology preferred