This career-track appointment is not eligible for tenure.
Visa sponsorship is not available for this position.
Outstanding U of A benefits include health, dental, and vision insurance plans; life insurance and disability programs; paid vacation, sick leave, and holidays; U of A/ASU/NAU tuition reduction for the employee and qualified family members; retirement plans; access to U of A recreation and cultural activities; and more!
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Duties & Responsibilities
Antifungal Discovery and Screening:
- Design, develop, and execute in vitro assays to identify and characterize small-molecule and biologic antifungal candidates against emerging viruses, including Cryptococcus neoformans, Candida auris, C. albicans, Coccidioides immitus, and Aspergillus fumigatus.
In Vivo Evaluation of Antifungals:
- Conduct and oversee preclinical in vivo studies in relevant animal models to assess efficacy, pharmacokinetics, and safety of antifungal candidates.
Mechanistic mycology Studies:
- Investigate fungal replication, pathogenesis, and host-fungi interactions to inform rational drug design and optimization of antifungal therapeutics.
Collaboration and Project Management:
- Coordinate with multidisciplinary teams including medicinal chemists, structural biologists, and clinicians to advance antiviral projects from discovery to preclinical development.
Scientific Communication and Reporting:
- Prepare manuscripts, grant reports, and presentations to disseminate research findings and support funding and regulatory requirements.
Knowledge, Skills and Abilities:
- Strong knowledge of mycology, fungal replication mechanisms, and host-fungus interactions.
- Skilled in designing and performing in vitro antifungal assays, cell culture techniques, and molecular biology methods.
- Skilled in conducting and interpreting in vivo animal studies for infectious diseases, including efficacy and PK/PD evaluation.
- Ability to analyze, interpret, and present complex scientific data clearly in written and oral formats.
- Demonstrated skills in experimental design, troubleshooting, and independent problem-solving.
- Ability to work collaboratively in multidisciplinary teams and manage multiple projects effectively.
- Knowledge and familiarity with biosafety regulations and experience working in BSL-2/BSL-3 laboratory environments
Minimum Qualifications
- Ph. D. in Virology, Mycology, Microbiology, Biochemistry, or a related biomedical field, with at least 5 years of relevant research experience in antifungal drug discovery or molecular mycology.
- Demonstrated expertise in in vitro mycology assays and experience with in vivo animal models for infectious diseases are required.
- A strong track record of peer-reviewed publications and experience working in multidisciplinary research teams is expected.
Preferred Qualifications
- Prior experience in antifungal drug discovery and development.
- Experience working with high-containment fungi and in BSL-3 laboratory settings.
- Prior experience in antiviral development against fungal pathogens and familiarity with BSL-2/BSL-3 laboratory practices is highly desirable.
Rank: Assistant Professor
Tenure Information
Career-Track (CT)
FLSA: Exempt
Full Time/Part Time: Full Time
Number of Hours Worked per Week: 40
Job FTE: 1.0
Work Calendar: Fiscal
Job Category: Faculty
Benefits Eligible: Yes - Full Benefits
Rate of Pay: DOE
Compensation Type: salary at 1.0 full-time equivalency (FTE)
Type of criminal background check required: Name-based criminal background check (non-security sensitive)
Number of Vacancies: 1
Contact Information for Candidates
Hongmin Li I hli001@pharmacy.arizona.edu
Open Until Filled: Yes
Documents Needed to Apply: Curriculum Vitae (CV) and Cover Letter
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