instrumentation, experimental design, and proteomics data analysis. Candidates should possess strong expertise in protein biochemistry, molecular biology, and quantitative proteomics approaches. A strong record of original peer-reviewed publications, scientific leadership, communication, and interpersonal skills is required. Applicants must have a Ph.D. or M.D./Ph.D. degree.
Responsibilities may include conducting independent and collaborative research in structural proteomics, chemical biology, and mitochondrial biology; developing and implementing mass spectrometry-based workflows including chemical crosslinking mass spectrometry (XL-MS), quantitative proteomics, and protein interaction mapping; operating and maintaining advanced LC-MS/MS instrumentation; analyzing complex proteomics datasets; mentoring students and trainees; contributing to manuscript preparation, grant writing, and collaborative research projects.
The successful applicant will have an opportunity to establish and lead new structural proteomics and crosslinking mass spectrometry capabilities within a newly established research program; develop independent research projects at the interface of proteomics, structural biology, neuroscience, and reproductive biology; collaborate with investigators across Penn's structural biology, proteomics, mitochondrial biology, and neuroscience communities; receive mentorship in laboratory leadership, grant writing, project development, and career advancement; and contribute to high-impact interdisciplinary research programs.
Candidates should have demonstrated experience designing and executing independent research projects and working effectively within collaborative multidisciplinary teams. Experience with Orbitrap-based mass spectrometry platforms, quantitative proteomics workflows, and advanced proteomics software tools is required.
Preferred qualifications include expertise in chemical crosslinking mass spectrometry (XL-MS), structural proteomics, protein interaction mapping, chemical biology, development of novel analytical methodologies, and computational analysis of proteomics datasets. Experience with mitochondrial biology, neuroscience, reproductive biology, cryo-EM, or integrative structural biology is desirable but not required.
Qualifications
Ph.D. or M.D./Ph.D.
Application Instructions
To apply, visit https://apply.interfolio.com/187556
