Research Fellow (CSCB/OST)
Job Description
We are a fast-moving translational research lab driven by the need to develop curative therapies for chronic myeloid leukaemia (CML) and Asian-specific solid tumours including nasopharyngeal cancer. Our team combines leading-edge multi-omics single-cell profiling with AI/ML-guided discovery to uncover new mechanisms of targeted drug resistance, then rigorously validates these findings using state-of-the-art platforms including iPSC-based technologies, advanced in vitro systems, and in vivo models. Our current work spans global clinical biomarker studies to predict drug resistance at diagnosis, and next-generation therapeutic strategies to eliminate persistent leukaemia stem cells (LSCs) in minimal residual disease and prevent disease transformation- ranging from NK cell-based approaches to small molecule-targeting of high-risk epigenetic cell states we have identified.
Key Responsibilities
- Independently carry out the design and execution of experimental research required by the research component of the project.
- Design and execute experiments, ensuring high-quality and reproducible outcomes.
- Translate research findings into publications, presentations, and new research directions.
- Develop plans for independent research which could have a considerable influence and impact on the relevant field attracting research funding.
- Provide support for external grant/protocol development, study design and management of research activities.
- Provide guidance and mentorship to undergraduate students / research assistants, contributing to team development and scientific direction.
- Perform other related duties incidental to the work described therein.
Job Requirements
- PhD in a relevant scientific discipline (or equivalent postgraduate degree with strong research track record).
- Strong laboratory experimental experience; ability to work independently and rigorously.
- Experience with iPSC-based platforms, multi-colour flow cytometry, and mouse models.
- Solid grounding in the scientific context of the research area and confidence supporting diverse research activities.
- Proven publication track record (including high-impact outputs).
- Demonstrated and growing research independence, with initiative and ambition to build new directions.
- Excellent scientific writing, critical thinking, communication, and presentation skills.
We regret that only shortlisted candidates will be notified.
More Information
Location: Outram Campus
Organization: Duke-NUS Medical School
Department: Office of Research
Employee Referral Eligible: No
Job requisition ID: 32661
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