Primary Work Address: 418 E 71st St #21, New York, NY, 10021
Current
HHMI Employees, click here to apply via your Workday
account.
The laboratory of
Dr. Samara Reck-Peterson at Weill Cornell
Medicine in
New York, NY is looking for an accomplished
Research Scientist with expertise in fungal natural products
along with experience in mass spectrometry-based metabolomics and
data processing for targeted and non-targeted approaches. The
Reck-Peterson Lab studies the mechanisms of intracellular transport
at molecular, cellular, and organismal scales. Our research
addresses fundamental questions in cell biology with direct
relevance to human health and disease.
For application submission: Please submit your CV, a cover
letter describing your research experience and why you are
interested in this position, and contact information for three
references.
We use a wide range of approaches: protein biochemistry and in
vitro reconstitution, single-molecule biophysics, proteomics and
genomics, metabolomics, fungal genetics, evolutionary analysis,
mammalian cell culture, and state-of-the-art live-cell imaging.
Through collaborations, we use cryo-electron microscopy and
cryo-electron tomography to pursue structural studies of the
transport machinery. For more information about Dr. Samara
Reck-Peterson and the lab, please visit:
https://reckpetersonlab.org/
This role will contribute to the Reck-Peterson lab’s research
program on fungal biology and secondary metabolite production. The
lab discovered that peroxisomes in filamentous fungi move by
“hitchhiking” on early endosomes; through a genetic screen we
identified a putative protein linker between the two organelles and
found that organelle dynamics play a role in the production of
secondary metabolites. Current efforts are aimed at understanding
the cell biology of secondary metabolite production.
This is one of two high-ranking, non-Investigator roles within the
lab. Ideal candidates will be confident and comfortable in a
leadership role, have a strong desire to serve as a trusted
resource for other members of the lab, and contribute to the lab’s
culture of doing collaborative science.
What we provide:
- Competitive compensation and comprehensive benefits.
- A collaborative, diverse, and supportive research
environment.
- Access to cutting-edge facilities and core resources, including
collaborative access to cryo-electron microscopy and cryo-electron
tomography.
Flexible scheduling and mentorship tailored to your next career
stage.
What you’ll do:
- Research (approximately 80% effort). Support the
collaborative research environment and provide guidance on
technical and operational aspects of research.
- Develop, design, and implement research projects, and
coordinate specialized and novel research functions.
- Design and execute mass spectrometry-based metabolomics
experiments using targeted and non-targeted approaches; isolate,
analyze, and characterize natural products, including unknown
compounds.
- Identify methodological problems in research protocols and
develop and implement modifications to optimize experimental
results.
- Develop innovative techniques and data analysis pipelines
required to meet research goals, and use software applications to
assemble, manipulate, format, and perform statistical analyses of
complex data and to mine large metabolomic datasets.
- Conduct literature reviews to determine the most suitable
research methods, and routinely review research activities to
determine where new information, methods, or collaborations could
positively impact projects.
- Review available technology and assist in bringing appropriate
new technology into the laboratory; may prepare specifications for
equipment and supplies needed to support research.
- Prepare reports for presentation at scientific meetings and
manuscripts for publication; write and edit manuscripts, fellowship
applications, and portions of grants.
- Lab operations and mentoring (approximately 20% effort).
Mentor graduate students, postdoctoral fellows, Research
Associates, and other staff, and train lab members on specialized
research methods such as fungal biology and metabolomics.
- Configure, operate, and maintain specialized equipment, and
train others in its use as necessary.
- Serve as a senior member of the lab, acting as a resource for
both students and staff on a variety of issues, along with other
duties as assigned by the Principal Investigator.
- Hold sole responsibility for your own research project with
shared responsibility for other research projects and/or project
teams, including projects performed in collaboration with other
laboratories.
- Contribute to writing both manuscripts and grants.
What you bring:
- PhD in the chemical, biological, biomedical, or biochemical
sciences, or an MD degree.
- More than five years of independent research experience after
earning a PhD (minimum of four years required).
- A broad range of scientific experience and a strong publication
record.
- Expertise in secondary metabolism, including methods to isolate
and analyze natural products and to characterize unknown compounds.
Expertise in mass spectrometry.
- Experience with fungal secondary metabolites and fungal biology
is strongly preferred.
- Demonstrated expertise in scientific methods, tools, and
technologies, and the ability to understand and apply new concepts,
technologies, and methods to evolving research needs.
- Ability to critically review complex information to identify
insights and improvements.
- Ability to write, prepare, and present reports, manuscripts,
and findings to diverse audiences, including at scientific meetings
and conferences.
- Excels both as an independent thinker and as a collaborative
team member, with the ability to work independently.
- A strong desire to mentor and teach trainees of all
levels.
- Strong written and verbal communication skills and excellent
interpersonal skills.
Physical Requirements
Remaining in a normal seated or standing position for extended
periods of time; reaching and grasping by extending hand(s) or
arm(s); dexterity to manipulate objects with fingers, for example
using a keyboard; communication skills using the spoken word;
ability to see and hear within normal parameters; ability to move
about workspace. The position requires mobility, including the
ability to move materials weighing up to several pounds (such as a
laptop computer or tablet). Work may involve possible exposure to
malodorous vapors, low dose radiation, contamination by toxic
chemicals and acids and presence of carcinogenic substances.
Persons with disabilities may be able to perform the essential
duties of this position with reasonable accommodation. Requests for
reasonable accommodation will be evaluated on an individual
basis.
Please Note:
This job description sets forth the job’s principal duties,
responsibilities, and requirements; it should not be construed as
an exhaustive statement, however. Unless they begin with the word
“may,” the Essential Duties and Responsibilities described above
are “essential functions” of the job, as defined by the Americans
with Disabilities Act.
Compensation and Benefits
Our employees are compensated from a total rewards perspective in
many ways for their contributions to our mission, including
competitive pay, exceptional health benefits, retirement plans,
time off, and a range of recognition and wellness programs. Visit
our
Benefits at HHMI site to learn more.
Hiring Pay Range
$83,433.79 - $104,292.24
Pay Type:
Annual
The posted range reflects HHMI’s good faith estimate of the
anticipated hiring salary range for this role at the time of
posting. Actual hiring compensation is determined by a candidate’s
qualifications, experience, and internal equity.
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