Research Senior Technician - Comprehensive Cancer Center

The laboratory focuses on identifying predictive biomarkers of therapeutic response and mechanisms of treatment resistance in colorectal cancer. Research activities integrate patient-derived tissues, organoid culture platforms, metabolic analyses, advanced microscopy, and in vivo experimental models within a highly collaborative translational research environment.

• Culture and maintain colorectal cancer in vitro models (cancer cell lines, primary fibroblasts, and patient-derived organoid models)
• Process and handle patient-derived tissues and isolate peripheral blood mononuclear cells (PBMCs)
• Perform standard molecular and cellular biology techniques including western blotting, RT-qPCR, microscopy-based analyses, flow cytometry preparation, and metabolic bioassays
• Conduct functional assays including cell viability, proliferation, and clonogenic survival assays
• Support in vivo mouse studies including tumor cell injection, tumor growth monitoring, anesthesia procedures, irradiation experiments, and maintenance of syngeneic and xenograft models

MINIMUM REQUIRED QUALIFICATIONS: Bachelor's Degree or equivalent experience required; 4 years of relevant experience required with High School diploma or GED, 2 years of relevant experience required with Associate's Degree, or 0 years of relevant experience required with Bachelor's Degree.