Research Specialist B (Department of Obstetrics and Gynecology)

Job Description

The Nasioudis Lab in the PSOM Department of Obstetrics and Gynecology, is a newly established research laboratory dedicated to advancing translational research in gynecologic oncology, with a focus on developing innovative therapeutic strategies for gynecological malignancies.

We are seeking an experienced, dedicated, and detail-oriented Research Specialist to join this dynamic team. This position offers a unique opportunity to contribute to cutting-edge cancer research while gaining hands-on experience in both laboratory and preclinical methodologies. The successful candidate will support a wide range of experimental work, including cell culture, organoid modeling, and mouse model studies, while also assisting in lab setup and operations.

Job Responsibilities

• Design new experiments and contribute to research publications and presentations
• Maintain and passage human cell cultures
• Generate, passage, store, and treat patient-derived organoid models
• Assist in the management of a mouse colony, including care, drug administration via oral gavage, and dosing schedules
• Support surgical procedures to develop patient-derived xenografts (PDX)
• Measure tumor size in mice using palpation and ultrasound
• Perform necropsy and bio-bank tissue samples
• Assist with processing formalin-fixed paraffin-embedded (FFPE) tissue samples
• Participate in lab management, including ordering, organizing, and maintaining reagents, equipment, and protocols
• Provide scientific and technical guidance for ongoing projects
• Maintain organized laboratory records and ensure compliance with safety protocols
• Perform other duties as assigned

*Position contingent upon continued funding*

Qualifications

• Bachelor's degree and 1-3 years of laboratory experience or equivalent combination of education and experience

The ideal candidate will reflect the following experience:

• Experience working with mice in a rodent barrier facility
• Familiarity with drug administration via oral gavage and survival surgeries (preferred)
• Experience with necropsy and tissue banking (preferred)
• Experience generating and culturing patient-derived organoids (preferred)
• Proficiency in tissue culture, including human primary cells (preferred)
• Familiarity with basic laboratory techniques such as Western blotting and flow cytometry (preferred)
• Strong organizational skills and attention to detail
• Ability to maintain accurate and organized laboratory data
• Effective communication and teamwork skills
• Flexibility with work hours and ability to multitask in a fast-paced environment