Research Specialist C (Department of Cancer Biology)

Job Description Summary

The Carman Li laboratory in the Department of Cancer Biology at the University of Pennsylvania is hiring a Research Specialist C. The Li lab studies unexplored mechanisms and therapeutic opportunities of hereditary cancers, particularly BRCA1/2 breast cancers, with the ultimate goal of improving patient outcomes. We use advanced methodologies, including genetically engineered mouse models, organoid cultures, patient samples, and single-cell omics.

This is an excellent opportunity to learn a wide array of in vivo, in vitro, and molecular techniques, contribute to cutting-edge research, and help advance the frontiers of cancer biology. The Li lab values a supportive and collaborative environment. Former trainees mentored by Dr. Li have earned publication authorship and successfully transitioned to graduate/medical schools and industry positions.

Successful candidates will have a strong background in biology, be highly motivated, and have excellent organizational skills. Responsibilities include managing daily lab operations and contributing to research projects.

Position is contingent upon continued grant funding.

Job Responsibilities

• Manage lab operations (including ordering, inventory, organization, and maintenance of equipment and reagents) and develop protocols for research and regulatory compliance (e.g. animal protocols, bio-safety protocols, etc.).
• Contribute to research projects, including:
  • Mouse Work (e.g. husbandry, genotyping, experiments, sample collection and analyses)
  • 2D cell and 3D organoid cultures
  • Molecular, cell, and tissue analyses (DNA cloning, CRISPR/RNAi gene perturbation, DNA/RNA/protein analysis, flow cytometry, histology)
• Develops relationships with research partners, research sites, sales representatives, regulatory offices, and affiliated organizations as part of laboratory management
• Train and supervise staff, interface with existing postdoctoral fellows and students in the laboratory
• Other duties and responsibilities as assigned

Qualifications

• Bachelor of Science and 3 to 5 years of experience or equivalent combination of education and experience in relevant areas is required.
• Experience in all three of the following is required: lab management, mouse models of cancer, cell/organoid culture.
• Highly motivated, have a good work ethic, and work independently and as a team.
• Follow protocols with attention to detail.
• Produce accurate and high-quality work.
• Think creatively to solve problems.
• Excellent skills in communication, organization, and time management.

Position is contingent upon continued funding.

Job Location

Philadelphia, Pennsylvania

Department / School

Perelman School of Medicine

Pay Range

$57,500.00 - $75,000.00 Annual Rate