Research Specialist C (Department of Cancer Biology)

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Job Description Summary

The Carman Li laboratory (www.CarmanLiLab.org) in the Department of Cancer Biology at the University of Pennsylvania is hiring a Research Specialist C. The Li lab studies unexplored mechanisms and therapeutic opportunities of hereditary cancers, particularly BRCA1/2 breast cancers, with the ultimate goal of improving patient outcomes. We use advanced methodologies, including genetically engineered mouse models, organoid cultures, patient samples, and single-cell omics.

This is an excellent opportunity to learn a wide array of in vivo, in vitro, and molecular techniques, contribute to cutting-edge research, and help advance the frontiers of cancer biology. The Li lab values a supportive and collaborative environment.

Job Responsibilities

• Manage lab operations (including ordering, inventory, organization, and maintenance of equipment and reagents) and develop protocols for research and regulatory compliance (e.g. animal protocols, bio-safety protocols, etc.).
• Contribute to research projects, including: Mouse Work (e.g. husbandry, genotyping, experiments, sample collection and analyses); 2D cell and 3D organoid cultures; Molecular, cell, and tissue analyses (DNA cloning, CRISPR/RNAi gene perturbation, DNA/RNA/protein analysis, flow cytometry, histology)
• Develops relationships with research partners, research sites, sales representatives, regulatory offices, and affiliated organizations as part of laboratory management
• Train and supervise staff, interface with existing postdoctoral fellows and students in the laboratory
• Other duties and responsibilities as assigned

Qualifications

• Bachelor of Science and 3 to 5 years of experience or equivalent combination of education and experience in relevant areas is required.
• Experience in all three of the following is required: lab management, mouse models of cancer, cell/organoid culture.
• Highly motivated, have a good work ethic, and work independently and as a team.
• Follow protocols with attention to detail.
• Produce accurate and high-quality work.
• Think creatively to solve problems.
• Excellent skills in communication, organization, and time management.

Position is contingent upon continued funding.