Job Description Summary

The selected candidate will serve as a senior scientist and lab manager in the Goodman Lab for Synthetic Immunology. They will independently execute and optimize complex experimental workflows including flow cytometry, primary T cell engineering, and viral vector production; oversee lab operations and equipment; and contribute substantively to data interpretation, protocol development, and manuscript and grant preparation.

Position is contingent on grant funding support.

Job Responsibilities

Operate and maintain lab equipment including the flow cytometer; independently perform flow cytometry experiments; troubleshoot instrument issues; train all lab members on operation
Independently perform and optimize primary human T cell culture, activation, and lentiviral transduction; lead viral vector production (BSL-2 lentiviral and AAV)
Conduct molecular cloning (Gibson Assembly, Golden Gate, restriction-ligation) and prepare sequencing libraries for high-throughput genomics
Maintain lab organization, reagent inventory, and equipment; coordinate supply ordering, vendor relationships, and equipment service contracts
Perform and coordinate in vivo mouse experiments (tumor injections, measurements, organ harvests, IV T cell transfers); liaise with ULAR
Develop, document, and maintain lab protocols and SOPs (Benchling, Notion); onboard and train rotation students, postdocs, and undergrads
Contribute to data analysis and interpretation; support manuscript and grant preparation; present results at lab meetings
Other duties and responsibilities as assigned

Position is contingent on grant funding support.

Qualifications

Bachelor of Science and 3 to 5 years of experience or equivalent combination of education and experience is required.

Job Description Summary

Position is contingent on grant funding support.

Job Responsibilities

Operate and maintain lab equipment including the flow cytometer; independently perform flow cytometry experiments; troubleshoot instrument issues; train all lab members on operation
Independently perform and optimize primary human T cell culture, activation, and lentiviral transduction; lead viral vector production (BSL-2 lentiviral and AAV)
Conduct molecular cloning (Gibson Assembly, Golden Gate, restriction-ligation) and prepare sequencing libraries for high-throughput genomics
Maintain lab organization, reagent inventory, and equipment; coordinate supply ordering, vendor relationships, and equipment service contracts
Perform and coordinate in vivo mouse experiments (tumor injections, measurements, organ harvests, IV T cell transfers); liaise with ULAR
Develop, document, and maintain lab protocols and SOPs (Benchling, Notion); onboard and train rotation students, postdocs, and undergrads
Contribute to data analysis and interpretation; support manuscript and grant preparation; present results at lab meetings
Other duties and responsibilities as assigned

Position is contingent on grant funding support.

Qualifications

Bachelor of Science and 3 to 5 years of experience or equivalent combination of education and experience is required.

Job Description Summary

Position is contingent on grant funding support.

Job Responsibilities

Operate and maintain lab equipment including the flow cytometer; independently perform flow cytometry experiments; troubleshoot instrument issues; train all lab members on operation
Independently perform and optimize primary human T cell culture, activation, and lentiviral transduction; lead viral vector production (BSL-2 lentiviral and AAV)
Conduct molecular cloning (Gibson Assembly, Golden Gate, restriction-ligation) and prepare sequencing libraries for high-throughput genomics
Maintain lab organization, reagent inventory, and equipment; coordinate supply ordering, vendor relationships, and equipment service contracts
Perform and coordinate in vivo mouse experiments (tumor injections, measurements, organ harvests, IV T cell transfers); liaise with ULAR
Develop, document, and maintain lab protocols and SOPs (Benchling, Notion); onboard and train rotation students, postdocs, and undergrads
Contribute to data analysis and interpretation; support manuscript and grant preparation; present results at lab meetings
Other duties and responsibilities as assigned

Position is contingent on grant funding support.

Qualifications

Bachelor of Science and 3 to 5 years of experience or equivalent combination of education and experience is required.

Research Specialist C

University of Pennsylvania

University of Pennsylvania, Philadelphia, PA, USA