Scientific Director of Core

Job Description Summary

Individual will serve as Scientific Director of the Stem Cell and Xenograft Core. Individual will work within the Management Team to execute all services provided by Core. However, individual will have primary responsibilities for work involving normal and malignant hematopoiesis studies. This will include supervision of the Hematologic Malignancies Tissue Bank of the University of Pennsylvania, supervision of studies involving human immune reconstitution in highly immuncompromised mouse strains, engraftment and therapy studies of acute leukemia's and other projects that may arise. Additionally, individual will lead research studies to more fully describe immune re-constitution in human immune reconstituted animals. Individual will supervise laboratory staff collecting and receiving patient samples and oversee performance of flow cytometry studies on engrafted mice. Individual may participate in preparation of grants and manuscripts.

Provides leadership for research strategy and operations across a large school or complex interdisciplinary research center. Directs planning and execution of high-impact research initiatives, ensuring coordination of resources, policies, and collaborations across multiple programs. Partners with faculty leadership, central offices, and external organizations to align research priorities, secure resources, and advance long-term institutional goals.

Job Responsibilities

• Management of Hematologic Malignancies Tissue Bank.
• Interactions including project review and design consultation on use of samples from Tissue Bank.
• Oversight of human immune reconstitution studies in highly immuncompromised mice.
• Oversight and design of human AML xenotransplantation studies for Core users.
• Management and training of Core personnel
• Oversight of Core budget
• Oversees the day-to-day operations of assigned area including the supervision of departmental employees. Provide advice and guidance to faculty clinicians, and management of all clinical research personnel activity, to include the oversight and development of training initiatives, audit manuals, and standard operating procedures
• Collaborates with the administrative team on strategy development for all operational activities and ensures that appropriate strategies are aligned with institutional objectives. Develop best practices, methods, techniques, and operational standards for clinical research across the enterprise
• Ensure streamlined and standardized processes, eliminate redundancies and ensure sound financial stewardship of space, equipment and expenditures. Partner with research finance team and administration to manage clinical research budget/s.
• Develop and maintain collaborative partnerships. Act as a liaison between key stakeholder e.g., commercial partners, alumni, industry and legislators. Direct communication of priorities to ensure execution of goals and milestones through regular meetings, status updates, and other written communications
• Operationalize and oversee the data collection, archival and reporting of clinical trials metrics. Establish data collection methodologies, data validation, and the implementation of reporting technologies. Oversee internal audits to ensure adherence to quality standards, operational best practices, and to identify potential risks
• Other duties and responsibilities as assigned

Qualifications

• Bachelor of Science, Bachelor of Arts, and 7 to 10 years or Master of Science, Master of Arts, and 5 to 7 years of experience or equivalent combination of education and experience is required.

Position is contingent upon funding

Job Location

Philadelphia, Pennsylvania

Department / School

Perelman School of Medicine