Advertising Summary: Virginia Commonwealth University (VCU)
School of Medicine is a premier academic medical center located in
the heart of Richmond. Accounting for almost half of VCU’s
sponsored research, the School of Medicine is internationally
recognized for patient care and education. Virginia Commonwealth
University is an equal opportunity employer.
Unit: Massey Comprehensive Cancer Ctr MBU
Department: Massey Research Support
Duties & Responsibilities:
Position Summary:
We are seeking a highly motivated Senior Research Lab Technician to
support the lab’s translational cancer research program focused on
breast cancer and acute myeloid leukemia (AML). The position will
assist with laboratory research and daily operations, including
supporting in vitro and in vivo experiments, handling and
monitoring laboratory animals, maintaining and organizing equipment
and supplies, preparing specimens and laboratory materials,
managing inventory, and documenting research data. The Senior
Research Assistant will work closely with the PI, postdoctoral
fellows, graduate students, and other laboratory staff,
contributing both independently and collaboratively to the lab’s
research efforts while providing general technical and logistical
support.
This is a restricted position with no set end date; continued
employment is dependent upon project need, availability of funding,
and performance.
Core Responsibilities:
- Cell Culture: Maintain and expand a range of breast
cancer and AML cell lines, primary patient-derived samples, and
stem/progenitor cultures under sterile conditions, including
establishing and troubleshooting new cell culture systems.
Flow Cytometry: Design, execute, and analyze multi-color
flow cytometry panels for immunophenotyping, cancer stem cell
marker analysis (e.g., ALDH, surface markers), cell sorting (FACS)
coordination, and apoptosis/proliferation assays.
Animal Handling: Perform routine handling, breeding
colony maintenance, genotyping, tumor cell implantation
(orthotopic/xenograft), treatment dosing, and tissue harvesting in
mouse models of breast cancer and leukemia, in full compliance with
IACUC protocols.
Molecular & Biochemical Assays: Conduct Western
blotting, ELISA, qPCR, immunofluorescence/immunohistochemistry, and
standard molecular cloning as needed to support ongoing
projects.
Lab Records & Compliance: Maintain detailed,
audit-ready laboratory notebooks and electronic records; ensure
compliance with institutional biosafety, chemical hygiene, and
animal welfare regulations.
Lab Management: Order and manage laboratory supplies and
reagents, maintain shared equipment, and assist with training of
new lab members and rotation students.
Data Support: Assist with data organization, figure
preparation, and summarization of results for lab meetings,
manuscripts, and grant progress reports.
Qualifications:
Minimum Qualifications
- Bachelor’s degree in biology, Cell Biology, Immunology,
Biochemistry, or a related life science field or equivalent
experience.
- A minimum of 2-3 years of hands-on laboratory experience, with
demonstrated proficiency in mammalian cell culture technique,
including primary cell and cancer stem cell culture.
- Substantial experience with multi-parameter flow cytometry,
including panel design, sample preparation, and data analysis
(e.g., FlowJo).
- Direct, hands-on experience with small animal (mouse) handling,
including injections, tumor implantation, breeding colony
management, and tissue collection; prior IACUC protocol experience
strongly preferred.
- Strong organizational skills and meticulous record-keeping
habits, with the ability to work independently and manage multiple
concurrent projects.
- Excellent written and verbal communication skills, with the
ability to work collaboratively within a multidisciplinary research
team.
- Demonstrated ability to work in and foster an environment of
respect, professionalism and civility with a population of faculty,
staff, and students from all backgrounds and experiences, or a
commitment to do so as a staff member at VCU.
Preferred Qualifications
- Prior experience in a cancer biology, hematology/oncology, or
immunology research laboratory.
- Experience with cell sorting operation or coordination,
ELISA/Western blotting, qPCR, or basic molecular cloning.
- Familiarity with xenograft and patient-derived xenograft (PDX)
tumor models.
- Experience contributing to IACUC or IBC protocol preparation
and renewal.
Salary Range: $50,000-$70,000
Benefits : All full-time university staff are eligible for
VCU’s robust
benefits
package that includes comprehensive health benefits, paid annual
and holiday leave, generous tuition benefits, retirement planning
and savings options, tax-deferred annuity and cash match programs,
employee discounts, well-being resources, abundant opportunities
for career development and advancement, and more.
FLSA Exemption Status: Non-Exempt
Hours per Week: 40
Restricted Position: Yes
ORP Eligible: No
Flexible Work Arrangement: Fully Onsite
University Job Title: 3405S - Sr Lab/Research Technician
Senior
Contact Information:
Contact Name: Cheyenne
Taylor
Contact Email: Cheyenne.Taylor@vcuhealth.org