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"Technical Associate I, Spranger Lab"

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Technical Associate I, Spranger Lab

Staff

May 1, 2026

Location

Cambridge

MIT

Type

Staff / Administration

Required Qualifications

Bachelor’s in biology, biomedical sciences, or related
2+ years research lab experience
Mouse handling & genotyping
Flow cytometry
Histology & immunohistochemistry
Molecular biology techniques
Organizational & communication skills

Research Areas

Tumor-immune microenvironment
Glioblastoma
Cancer immunology
Murine brain tumor models
Neuro-oncology
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Technical Associate I, Spranger Lab

Posting Description

TECHNICAL ASSOCIATE I, SPRANGER LAB, Koch Institute for Integrated Cancer Research, to support research investigating the tumor–immune microenvironment of glioblastoma. This position will support research on the tumor immune microenvironment of glioblastoma, focusing on how immune responses evolve during tumor development and following therapy using murine models and immunologic approaches. Responsibilities include supporting mouse brain tumor studies such as genotyping, tumor induction, drug administration, survival monitoring, and tissue collection in accordance with approved animal protocols. The technician will perform immune and molecular assays including flow cytometry, histology, immunohistochemistry, cloning, and sample processing. The role involves executing experiments independently, maintaining detailed laboratory records, organizing and entering data, managing reagents and inventory, ordering supplies, maintaining equipment, and ensuring compliance with research protocols. Additional duties include assisting with literature searches and supporting the preparation of figures, reports, and research summaries. The technician will work closely with a physician scientist postdoctoral fellow.

Job Requirements

REQUIRED: Bachelor’s degree in biology, biomedical sciences, chemistry, or a related field; a minimum of two years of research laboratory experience, including undergraduate experience; experience or strong interest in immunology or cancer biology, mouse handling and genotyping, flow cytometry, histology or immunohistochemistry, or basic molecular biology; strong organizational and communication skills; attention to detail; ability to work independently and as part of a team; and familiarity with laboratory safety practices. PREFERRED: Experience with mouse models, flow cytometry, tissue culture, cancer immunology, neuro-oncology, or translational research, and interest in contributing to experimental design and data interpretation.

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Frequently Asked Questions

🎓What qualifications are required for the Technical Associate I position in Spranger Lab?

This role requires a Bachelor’s degree in biology, biomedical sciences, chemistry, or related field, plus a minimum of two years of research laboratory experience (including undergraduate). Key skills include mouse handling and genotyping, flow cytometry, histology or immunohistochemistry, and basic molecular biology. Strong organizational skills, attention to detail, and lab safety familiarity are essential. Explore research assistant jobs for similar roles.

🔬What are the main responsibilities in this glioblastoma research role?

Responsibilities include supporting mouse brain tumor studies (genotyping, tumor induction, drug administration, survival monitoring, tissue collection per protocols), performing immune and molecular assays like flow cytometry, histology, immunohistochemistry, cloning, and sample processing. Additional duties: lab records, data organization, reagent management, equipment maintenance, and assisting with literature searches and figures. Work closely with a postdoctoral fellow in the Spranger Lab. See clinical research jobs for related opportunities.

What preferred experience is ideal for this cancer immunology technician position?

Preferred: Experience with mouse models, flow cytometry, tissue culture, cancer immunology, neuro-oncology, or translational research. Interest in experimental design and data interpretation is a plus. A strong interest in immunology or cancer biology is highly valued. Check postdoctoral research tips for career growth.

📝How do I apply for the Technical Associate I role at MIT Koch Institute?

Applications are open until the expiration date of May 1, 2026. Submit via MIT’s job portal linked in the posting. Ensure your resume highlights lab experience, mouse handling, and relevant skills. Prepare for compliance with animal protocols. Use our free resume template and cover letter template to stand out.

🧬What is the research focus of the Spranger Lab at Koch Institute?

The lab investigates the tumor–immune microenvironment of glioblastoma, focusing on immune response evolution during tumor development and therapy using murine models and immunologic approaches. This Technical Associate I role supports key experiments in cancer biology and immunology. Learn more about research jobs in higher ed.

Is this position suitable for those new to mouse models or flow cytometry?

A minimum of two years lab experience is required, with experience or strong interest in mouse handling/genotyping, flow cytometry, or related skills. Undergraduate experience counts. If building skills, review research assistant advice adaptable to US roles like this at MIT.
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