About the Project
TRIM21 is the cytosolic E3 ligase and antibody receptor responsible for intracellular antibody immunity. Unlike other ubiquitin ligases, TRIM21 doesn’t have a defined substrate but is directed towards its targets by antibodies. This unusual mechanism allows TRIM21 to target highly diverse substrates from bacteria and viruses to neurodegenerative aggregates and protein complexes. This diverse activity allows TRIM21 to prevent fatal viral infection or inhibit the accumulation of tau aggregates.…
This is a Preview Listing…
You must sign in to see the full job description, and to apply.
Manage / Upgrade this job to a Full Job Listing.
Find Your Best Opportunity
Tell them AcademicJobs.com sent you!