The Downtown Campus, also known as Polk Street Campus, emphasizes continuing education, workforce development, and short-term training programs in the heart of Amarillo's business district. It provides flexible scheduling for working adults seeking skill enhancement and professional certifications.
The East Campus focuses on advanced technical and vocational training, particularly in transportation, manufacturing, and aviation fields, utilizing facilities from the former Amarillo Air Force Base for hands-on instruction near the airport.
The Everett and Mabel McDougal Hinkson Memorial Campus in Hereford serves Deaf Smith County with core academic transfer courses, general education, and select vocational programs tailored to regional agricultural and community needs.
The Moore County Campus in Dumas provides accessible higher education to the Texas Panhandle region, offering associate degrees, general studies, and preparatory courses for transfer or local employment in a supportive rural setting.
The Moore County Career & Technical Center specializes in hands-on vocational training aligned with local industry demands, particularly in manufacturing, energy, and technical trades to prepare students for immediate workforce entry.
The Washington Street Campus serves as the flagship location of Amarillo College, offering a comprehensive range of core academic programs designed for transfer to four-year universities and foundational career preparation. It hosts a variety of liberal arts, sciences, and professional studies with modern facilities including libraries, labs, and performance halls.
The West Campus specializes in health sciences and allied health programs, located near Amarillo's hospital district to facilitate clinical training and partnerships with medical facilities. It focuses on workforce-ready certificates and associate degrees in healthcare professions.