A. Hari Reddi

A. Hari Reddi is Professor Emeritus in the Department of Orthopaedic Surgery at the University of California, Davis School of Medicine. He joined UC Davis in 1997 as the inaugural holder of the Lawrence J. Ellison Endowed Chair in Musculoskeletal Molecular Biology, a position he held as Distinguished Professor of Orthopedics. Previously, from 1991 to 1997, he served as the Virginia M. and William A. Percy Chair and Professor in Orthopaedic Surgery, Professor of Biological Chemistry, and Professor of Oncology at Johns Hopkins University School of Medicine. Earlier in his career, Reddi was Chief of the Bone Cell Biology Section at the National Institutes of Health from 1977 to 1991 and Assistant Professor at the Ben May Laboratory for Cancer Research at the University of Chicago from 1972 to 1977. His research spans over four decades and centers on bone and cartilage regeneration and tissue engineering within the field of Medicine.

Reddi pioneered the identification and characterization of bone morphogenetic proteins (BMPs) and their role in stimulating new bone growth, demonstrating how morphogens bound to extracellular matrix scaffolds collaborate with stem cells to form cartilage and bone. His specific interests include stem cells for chondrogenesis isolated from bone marrow, muscle, and synovium; tissue engineering and regeneration of articular cartilage; and engineering lubrication in tissue-engineered cartilage. BMPs from his research are utilized worldwide for healing bone fractures, vertebral fusions in spine surgery, craniofacial bone regeneration, and injuries sustained by U.S. military personnel. He has received the inaugural Marshall R. Urist Award from the Orthopaedic Research Society in 1997, the Nicolas Andry Award from the Association of Bone and Joint Surgeons in 1999, and was elected a Fellow of the National Academy of Inventors in 2015. Reddi holds six patents and has authored over 300 peer-reviewed publications, including seminal papers such as 'Dissociative extraction and reconstitution of extracellular matrix components involved in local bone differentiation' (Proceedings of the National Academy of Sciences, 1981), 'Purification and partial amino acid sequence of osteogenin, a protein initiating bone differentiation' (Journal of Biological Chemistry, 1989), and 'Pulsed Electromagnetic Fields and Tissue Engineering of the Joints' (Tissue Engineering Part B Reviews, 2018). His work has had a profound impact on musculoskeletal molecular biology and regenerative medicine.

Professional Email: ahreddi@ucdavis.edu