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Andrea Cipriani is Professor of Psychiatry and NIHR Research Professor at the Department of Psychiatry, University of Oxford. He holds an MD from the University of Padua and a PhD from the University of Verona. Cipriani serves as Honorary Consultant Psychiatrist at Oxford Health NHS Foundation Trust, Director of the Global Alliance for Living Evidence on Depression, Anxiety and Psychosis (GALENOS), Director of the NIHR Oxford Health Clinical Research Facility, Lead of the Data Science Theme at the Oxford Health Biomedical Research Centre, and Lead of the Oxford Precision Psychiatry Lab. His research centres on evidence synthesis methodologies, including systematic reviews, meta-analyses and network meta-analyses of pharmacological and non-pharmacological interventions for major depression, bipolar disorder and psychosis. These studies have informed clinical guidelines in multiple countries and contributed to treatment recommendations in low- and middle-income settings. Cipriani has also advanced precision psychiatry through the development of the PETRUSHKA decision-support tool and the ongoing PRADA project, which incorporate patient data, machine learning and genetic predictors to personalise antidepressant treatment. He is Editor in Chief of BMJ Mental Health and serves on the Editorial Board of The Lancet Psychiatry. Cipriani collaborates with international institutions and organisations including NICE, the European Medicines Agency, WHO and the United Nations.
Cipriani leads multidisciplinary projects that integrate human and animal studies, lived experience and industry input to address key challenges in mental health research. His work on living evidence synthesis through GALENOS emphasises dynamic, open-access updates to findings. He has contributed to numerous high-impact publications on topics such as dose-response relationships of antidepressants, pharmacological interventions for ADHD and decision-support systems for major depressive disorder. Cipriani maintains an extensive publication record exceeding 500 outputs and continues to influence evidence-based practice and personalised care in psychiatry through his academic appointments, editorial roles and research leadership at the University of Oxford.
University of Oxford's PETRUSHKA AI tool, backed by NIHR, cuts antidepressant dropouts by 40% and improves symptoms. Explore the trial, implications for UK mental health research.
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