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5.04/23/2026

Always approachable and easy to talk to.

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About Anupriya

Dr. Anupriya Gupta is a Postdoctoral Fellow in the Department of Microbiology and Immunology, Faculty of Biomedical Sciences, at the University of Otago. She joined the Pletzer Lab in 2024 on a Marsden-funded project dedicated to investigating host immune responses to polymicrobial skin infections caused by Staphylococcus aureus and Pseudomonas aeruginosa. Employing murine skin abscess models, bulk and single-cell RNA sequencing, and cytokine profiling, her research examines how pathogen-pathogen interactions modulate immune activation, disease severity, and therapeutic outcomes. Key findings demonstrate that co-infections produce larger abscesses accompanied by suppressed pro-inflammatory cytokine expression and reduced inflammatory signaling at the cellular level. Instead, there is upregulation of genes associated with epithelial defense and barrier repair, suggesting a host strategy prioritizing tissue protection and antimicrobial containment over classical inflammation. This work aims to uncover mechanisms for enhancing treatments against complex skin and soft tissue infections, which pose significant clinical challenges due to increased severity and resistance.

Rate My Professor Anupriya Gupta | University of Otago